BRD-K05804044_AZ-628_HA1E_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

77 genes differentially expressed following the BRD-K05804044_AZ-628_HA1E_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AKR1C1 aldo-keto reductase family 1, member C1
AOC3 amine oxidase, copper containing 3
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
BMP4 bone morphogenetic protein 4
C7 complement component 7
CD24 CD24 molecule
CDC42 cell division cycle 42
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFLAR CASP8 and FADD-like apoptosis regulator
CHRDL1 chordin-like 1
CLU clusterin
CNN1 calponin 1, basic, smooth muscle
CSTA cystatin A (stefin A)
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL13 chemokine (C-X-C motif) ligand 13
DLK1 delta-like 1 homolog (Drosophila)
DUSP1 dual specificity phosphatase 1
EDN1 endothelin 1
EFS embryonal Fyn-associated substrate
EGF epidermal growth factor
EIF5A eukaryotic translation initiation factor 5A
FILIP1L filamin A interacting protein 1-like
FMO2 flavin containing monooxygenase 2 (non-functional)
GADD45B growth arrest and DNA-damage-inducible, beta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOPX HOP homeobox
ICAM1 intercellular adhesion molecule 1
IFI27 interferon, alpha-inducible protein 27
ILK integrin-linked kinase
KRT15 keratin 15, type I
KRT19 keratin 19, type I
KRT8 keratin 8, type II
L1CAM L1 cell adhesion molecule
LMOD1 leiomodin 1 (smooth muscle)
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MFAP5 microfibrillar associated protein 5
NCAM1 neural cell adhesion molecule 1
NTS neurotensin
PERP PERP, TP53 apoptosis effector
PLAGL1 pleiomorphic adenoma gene-like 1
PROM1 prominin 1
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
REEP1 receptor accessory protein 1
S100P S100 calcium binding protein P
TBL1X transducin (beta)-like 1X-linked
TM4SF1 transmembrane 4 L six family member 1
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TOX3 TOX high mobility group box family member 3
TPD52L1 tumor protein D52-like 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon

decreased expression

Symbol Name
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL6A1 collagen, type VI, alpha 1
COL6A2 collagen, type VI, alpha 2
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
F13A1 coagulation factor XIII, A1 polypeptide
FOSL1 FOS-like antigen 1
HMGA2 high mobility group AT-hook 2
HMOX1 heme oxygenase 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MOK MOK protein kinase
NRP1 neuropilin 1
OLFML2B olfactomedin-like 2B
PLEC plectin
R3HDM4 R3H domain containing 4
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC39A6 solute carrier family 39 (zinc transporter), member 6
SOX9 SRY (sex determining region Y)-box 9
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)