BRD-K05562558_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K05562558_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALOX5AP arachidonate 5-lipoxygenase-activating protein
C14ORF132 chromosome 14 open reading frame 132
CA2 carbonic anhydrase II
CBR1 carbonyl reductase 1
CLIC4 chloride intracellular channel 4
CRABP1 cellular retinoic acid binding protein 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DRAM1 DNA-damage regulated autophagy modulator 1
FHL1 four and a half LIM domains 1
GCLM glutamate-cysteine ligase, modifier subunit
HACD1 3-hydroxyacyl-CoA dehydratase 1
HIST1H1C histone cluster 1, H1c
HK1 hexokinase 1
HMOX1 heme oxygenase 1
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IGFBP6 insulin-like growth factor binding protein 6
IL32 interleukin 32
IRS2 insulin receptor substrate 2
KIAA0101 KIAA0101
MAP7 microtubule-associated protein 7
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
NEFL neurofilament, light polypeptide
NEFM neurofilament, medium polypeptide
NFE2 nuclear factor, erythroid 2
NQO1 NAD(P)H dehydrogenase, quinone 1
OXTR oxytocin receptor
PHACTR2 phosphatase and actin regulator 2
PLIN2 perilipin 2
RHOB ras homolog family member B
SCGB2A2 secretoglobin, family 2A, member 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC38A1 solute carrier family 38, member 1
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TCAF1 TRPM8 channel-associated factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TTC39A tetratricopeptide repeat domain 39A
TUSC3 tumor suppressor candidate 3
TXN thioredoxin
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AHNAK2 AHNAK nucleoprotein 2
C7 complement component 7
CASP7 caspase 7, apoptosis-related cysteine peptidase
CFLAR CASP8 and FADD-like apoptosis regulator
CHL1 cell adhesion molecule L1-like
CHRDL1 chordin-like 1
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CYTH1 cytohesin 1
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
ERAP1 endoplasmic reticulum aminopeptidase 1
FGFR3 fibroblast growth factor receptor 3
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KRT81 keratin 81, type II
LCN2 lipocalin 2
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MDK midkine (neurite growth-promoting factor 2)
MUC16 mucin 16, cell surface associated
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NR1H2 nuclear receptor subfamily 1, group H, member 2
OLFM4 olfactomedin 4
PCSK1 proprotein convertase subtilisin/kexin type 1
PLAU plasminogen activator, urokinase
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS5 ribosomal protein S5
SFRP1 secreted frizzled-related protein 1
SLIT2 slit homolog 2 (Drosophila)
STC1 stanniocalcin 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
ZNF264 zinc finger protein 264
ZNF586 zinc finger protein 586