BRD-K05549170_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K05549170_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACPP acid phosphatase, prostate
ANOS1 anosmin 1
AREG amphiregulin
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ASPN asporin
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CADM1 cell adhesion molecule 1
COMP cartilage oligomeric matrix protein
CXCL14 chemokine (C-X-C motif) ligand 14
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR4 chemokine (C-X-C motif) receptor 4
DLC1 DLC1 Rho GTPase activating protein
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP22 dual specificity phosphatase 22
FGFR3 fibroblast growth factor receptor 3
FRZB frizzled-related protein
GJA1 gap junction protein, alpha 1, 43kDa
GPC3 glypican 3
HIST1H2AC histone cluster 1, H2ac
JAG1 jagged 1
KRT14 keratin 14, type I
KRT5 keratin 5, type II
LCN2 lipocalin 2
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MEIS2 Meis homeobox 2
METTL7A methyltransferase like 7A
NPY neuropeptide Y
PERP PERP, TP53 apoptosis effector
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PTN pleiotrophin
RGCC regulator of cell cycle
SFN stratifin
SGK1 serum/glucocorticoid regulated kinase 1
STEAP1 six transmembrane epithelial antigen of the prostate 1
TBC1D4 TBC1 domain family, member 4
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TUSC3 tumor suppressor candidate 3
VTCN1 V-set domain containing T cell activation inhibitor 1
WASF3 WAS protein family, member 3

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
ANKRD36B ankyrin repeat domain 36B
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
BASP1 brain abundant, membrane attached signal protein 1
CDK12 cyclin-dependent kinase 12
CHD9 chromodomain helicase DNA binding protein 9
DLK1 delta-like 1 homolog (Drosophila)
DUSP3 dual specificity phosphatase 3
ELANE elastase, neutrophil expressed
EMX2 empty spiracles homeobox 2
FAM46A family with sequence similarity 46, member A
FAM57A family with sequence similarity 57, member A
FHL2 four and a half LIM domains 2
GRAMD3 GRAM domain containing 3
ISG15 ISG15 ubiquitin-like modifier
LONP2 lon peptidase 2, peroxisomal
LYST lysosomal trafficking regulator
METRN meteorin, glial cell differentiation regulator
NT5E 5'-nucleotidase, ecto (CD73)
PLAC8 placenta-specific 8
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
SCAND1 SCAN domain containing 1
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TARBP1 TAR (HIV-1) RNA binding protein 1
TOX3 TOX high mobility group box family member 3
TXNL4B thioredoxin-like 4B
ZNF131 zinc finger protein 131