BRD-K05396879_15-delta prostaglandin J2_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

43 genes differentially expressed following the BRD-K05396879_15-delta prostaglandin J2_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
ADM adrenomedullin
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FOSL1 FOS-like antigen 1
GCLC glutamate-cysteine ligase, catalytic subunit
GPX2 glutathione peroxidase 2
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGLL1 immunoglobulin lambda-like polypeptide 1
LMO4 LIM domain only 4
NR0B1 nuclear receptor subfamily 0, group B, member 1
PDE4D phosphodiesterase 4D, cAMP-specific
PKP1 plakophilin 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
TGFBI transforming growth factor, beta-induced, 68kDa
WNT5A wingless-type MMTV integration site family, member 5A

decreased expression

Symbol Name
BAMBI BMP and activin membrane-bound inhibitor
CTSH cathepsin H
DEPTOR DEP domain containing MTOR-interacting protein
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
ESR1 estrogen receptor 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATA3 GATA binding protein 3
IL33 interleukin 33
MARCKSL1 MARCKS-like 1
MLPH melanophilin
NFIB nuclear factor I/B
NREP neuronal regeneration related protein
POSTN periostin, osteoblast specific factor
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
SOX4 SRY (sex determining region Y)-box 4
TMC5 transmembrane channel-like 5
TMEM164 transmembrane protein 164
VCAN versican