BRD-K05197617_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

115 genes differentially expressed following the BRD-K05197617_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5 arachidonate 5-lipoxygenase
ARMCX3 armadillo repeat containing, X-linked 3
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
BANK1 B-cell scaffold protein with ankyrin repeats 1
CALU calumenin
CCL20 chemokine (C-C motif) ligand 20
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKAP4 cytoskeleton-associated protein 4
CLC Charcot-Leyden crystal galectin
CLEC11A C-type lectin domain family 11, member A
CREB3L2 cAMP responsive element binding protein 3-like 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DEFA4 defensin, alpha 4, corticostatin
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DUSP1 dual specificity phosphatase 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ELANE elastase, neutrophil expressed
FKBP11 FK506 binding protein 11, 19 kDa
FKBP14 FK506 binding protein 14, 22 kDa
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLRX glutaredoxin (thioltransferase)
H1F0 H1 histone family, member 0
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HYOU1 hypoxia up-regulated 1
IFRD1 interferon-related developmental regulator 1
LCN2 lipocalin 2
LMO4 LIM domain only 4
LTF lactotransferrin
MBNL2 muscleblind-like splicing regulator 2
MID1IP1 MID1 interacting protein 1
MINK1 misshapen-like kinase 1
MMP12 matrix metallopeptidase 12
MPO myeloperoxidase
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)
NUCB2 nucleobindin 2
PDIA4 protein disulfide isomerase family A, member 4
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
PSAT1 phosphoserine aminotransferase 1
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RND3 Rho family GTPase 3
RNF167 ring finger protein 167
S100A12 S100 calcium binding protein A12
S100P S100 calcium binding protein P
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial)
SRGN serglycin
STC2 stanniocalcin 2
TBX3 T-box 3
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TMEM100 transmembrane protein 100
TMEM45A transmembrane protein 45A
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
VCAN versican
WARS tryptophanyl-tRNA synthetase
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble

decreased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD2 abhydrolase domain containing 2
AK4 adenylate kinase 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
APOD apolipoprotein D
CD93 CD93 molecule
CHRDL1 chordin-like 1
CNPY3 canopy FGF signaling regulator 3
COL4A2 collagen, type IV, alpha 2
CTSH cathepsin H
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL9 chemokine (C-X-C motif) ligand 9
EGR2 early growth response 2
ESR1 estrogen receptor 1
FDFT1 farnesyl-diphosphate farnesyltransferase 1
GLUL glutamate-ammonia ligase
GPM6A glycoprotein M6A
GPRC5A G protein-coupled receptor, class C, group 5, member A
IGFBP6 insulin-like growth factor binding protein 6
INSIG1 insulin induced gene 1
JCHAIN joining chain of multimeric IgA and IgM
KANK1 KN motif and ankyrin repeat domains 1
KRT19 keratin 19, type I
LDLR low density lipoprotein receptor
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAGEA12 melanoma antigen family A12
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MEIS1 Meis homeobox 1
MFAP5 microfibrillar associated protein 5
NPY1R neuropeptide Y receptor Y1
NRCAM neuronal cell adhesion molecule
NRIP1 nuclear receptor interacting protein 1
NRN1 neuritin 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
RUFY3 RUN and FYVE domain containing 3
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEPP1 selenoprotein P, plasma, 1
SQLE squalene epoxidase
TFF3 trefoil factor 3 (intestinal)
TLR4 toll-like receptor 4
TMEM14A transmembrane protein 14A
TSPAN8 tetraspanin 8
XBP1 X-box binding protein 1
ZFPM2 zinc finger protein, FOG family member 2