BRD-K05197617_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K05197617_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF4 activating transcription factor 4
CYB561 cytochrome b561
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
FKBP11 FK506 binding protein 11, 19 kDa
GLRX glutaredoxin (thioltransferase)
GULP1 GULP, engulfment adaptor PTB domain containing 1
GUSBP11 glucuronidase, beta pseudogene 11
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA13 heat shock protein 70kDa family, member 13
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IGKC immunoglobulin kappa constant
LAMP5 lysosomal-associated membrane protein family, member 5
MTDH metadherin
PNKP polynucleotide kinase 3'-phosphatase
SDC2 syndecan 2
SDF2L1 stromal cell-derived factor 2-like 1
SEC24D SEC24 family member D
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SLC33A1 solute carrier family 33 (acetyl-CoA transporter), member 1
STC2 stanniocalcin 2
TWF2 twinfilin actin binding protein 2
UBE2J1 ubiquitin-conjugating enzyme E2, J1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ADGRG6 adhesion G protein-coupled receptor G6
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AK4 adenylate kinase 4
AREG amphiregulin
ARID5B AT rich interactive domain 5B (MRF1-like)
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD44 CD44 molecule (Indian blood group)
CHEK1 checkpoint kinase 1
CXADR coxsackie virus and adenovirus receptor
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
FERMT1 fermitin family member 1
FGFR3 fibroblast growth factor receptor 3
GLUL glutamate-ammonia ligase
GPX2 glutathione peroxidase 2
MACF1 microtubule-actin crosslinking factor 1
PPT1 palmitoyl-protein thioesterase 1
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTHLH parathyroid hormone-like hormone
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SIK1 salt-inducible kinase 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SOX9 SRY (sex determining region Y)-box 9
STK26 serine/threonine protein kinase 26
TRIB2 tribbles pseudokinase 2
WT1 Wilms tumor 1