BRD-K05197617_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K05197617_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
CHIC2 cysteine-rich hydrophobic domain 2
DHRS2 dehydrogenase/reductase (SDR family) member 2
GDF15 growth differentiation factor 15
GLRX glutaredoxin (thioltransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
LOC100505650 uncharacterized LOC100505650
MAP7 microtubule-associated protein 7
PDIA3 protein disulfide isomerase family A, member 3
PDIA6 protein disulfide isomerase family A, member 6
PLAT plasminogen activator, tissue
RCAN1 regulator of calcineurin 1
SDF2L1 stromal cell-derived factor 2-like 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SQSTM1 sequestosome 1
TESC tescalcin
TMEM2 transmembrane protein 2
TMX4 thioredoxin-related transmembrane protein 4
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TTC39A tetratricopeptide repeat domain 39A
TUBA1A tubulin, alpha 1a
WIPI1 WD repeat domain, phosphoinositide interacting 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
CERS6 ceramide synthase 6
COLEC12 collectin sub-family member 12
DNTTIP2 deoxynucleotidyltransferase, terminal, interacting protein 2
DUSP6 dual specificity phosphatase 6
EIF1AX eukaryotic translation initiation factor 1A, X-linked
FAM60A family with sequence similarity 60, member A
FOLR1 folate receptor 1 (adult)
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KLF4 Kruppel-like factor 4 (gut)
MOB1A MOB kinase activator 1A
NELL2 NEL-like 2 (chicken)
PODXL podocalyxin-like
RRP8 ribosomal RNA processing 8, methyltransferase, homolog (yeast)
S100A8 S100 calcium binding protein A8
SDC2 syndecan 2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SRGN serglycin
TXNIP thioredoxin interacting protein
VSNL1 visinin-like 1
XIST X inactive specific transcript (non-protein coding)
ZNF586 zinc finger protein 586