BRD-K05114711_-666_MCF7_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

69 genes differentially expressed following the BRD-K05114711_-666_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AREG amphiregulin
ASNS asparagine synthetase (glutamine-hydrolyzing)
CCL5 chemokine (C-C motif) ligand 5
CD8A CD8a molecule
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTGF connective tissue growth factor
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DACH1 dachshund family transcription factor 1
DAPK1 death-associated protein kinase 1
DDIT4 DNA-damage-inducible transcript 4
DUSP4 dual specificity phosphatase 4
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FZD10 frizzled class receptor 10
GAS6 growth arrest-specific 6
GUSBP11 glucuronidase, beta pseudogene 11
IFI27 interferon, alpha-inducible protein 27
IFITM1 interferon induced transmembrane protein 1
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL32 interleukin 32
JCHAIN joining chain of multimeric IgA and IgM
KLF6 Kruppel-like factor 6
KRT7 keratin 7, type II
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OLFM4 olfactomedin 4
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PSAT1 phosphoserine aminotransferase 1
SOX4 SRY (sex determining region Y)-box 4
SOX9 SRY (sex determining region Y)-box 9
SQSTM1 sequestosome 1
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
ZNF91 zinc finger protein 91

decreased expression

Symbol Name
AGR2 anterior gradient 2
ATAD2 ATPase family, AAA domain containing 2
BDH1 3-hydroxybutyrate dehydrogenase, type 1
BIRC5 baculoviral IAP repeat containing 5
CAV1 caveolin 1, caveolae protein, 22kDa
CCNA2 cyclin A2
CENPM centromere protein M
CLU clusterin
COL5A2 collagen, type V, alpha 2
CSRP2 cysteine and glycine-rich protein 2
DCXR dicarbonyl/L-xylulose reductase
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ETNK1 ethanolamine kinase 1
EXOSC4 exosome component 4
FASN fatty acid synthase
GINS2 GINS complex subunit 2 (Psf2 homolog)
GJA1 gap junction protein, alpha 1, 43kDa
HOXB2 homeobox B2
HOXB7 homeobox B7
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IRS1 insulin receptor substrate 1
MRPS7 mitochondrial ribosomal protein S7
MUC1 mucin 1, cell surface associated
NQO1 NAD(P)H dehydrogenase, quinone 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
SEPW1 selenoprotein W, 1
SMAD1 SMAD family member 1
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12)
STRA13 stimulated by retinoic acid 13
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
ZWINT ZW10 interacting kinetochore protein