BRD-K05114711_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-K05114711_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
CD163 CD163 molecule
CXCL14 chemokine (C-X-C motif) ligand 14
DDIT4 DNA-damage-inducible transcript 4
FBN2 fibrillin 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
INSIG1 insulin induced gene 1
MFAP5 microfibrillar associated protein 5
PDGFRL platelet-derived growth factor receptor-like
RFC5 replication factor C (activator 1) 5, 36.5kDa
SQSTM1 sequestosome 1
UBE2B ubiquitin-conjugating enzyme E2B

decreased expression

Symbol Name
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
CD24 CD24 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CST7 cystatin F (leukocystatin)
FOLR1 folate receptor 1 (adult)
MPO myeloperoxidase
NDNF neuron-derived neurotrophic factor
NME4 NME/NM23 nucleoside diphosphate kinase 4
PCCB propionyl CoA carboxylase, beta polypeptide
POSTN periostin, osteoblast specific factor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SFTPA2 surfactant protein A2
SMAD3 SMAD family member 3
TFPI2 tissue factor pathway inhibitor 2
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TM4SF1 transmembrane 4 L six family member 1
WNT5A wingless-type MMTV integration site family, member 5A