BRD-K05104363_PD-184352_MDAMB231_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

73 genes differentially expressed following the BRD-K05104363_PD-184352_MDAMB231_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOE apolipoprotein E
BST2 bone marrow stromal cell antigen 2
CA12 carbonic anhydrase XII
COL3A1 collagen, type III, alpha 1
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FXYD2 FXYD domain containing ion transport regulator 2
GAS1 growth arrest-specific 1
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
H1F0 H1 histone family, member 0
HSPB8 heat shock 22kDa protein 8
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
LITAF lipopolysaccharide-induced TNF factor
MEIS2 Meis homeobox 2
MGP matrix Gla protein
PDGFD platelet derived growth factor D
PECR peroxisomal trans-2-enoyl-CoA reductase
PLTP phospholipid transfer protein
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBP1 retinol binding protein 1, cellular
RRAGD Ras-related GTP binding D
S100A2 S100 calcium binding protein A2
SEPW1 selenoprotein W, 1
WBP5 WW domain binding protein 5

decreased expression

Symbol Name
ADRB2 adrenoceptor beta 2, surface
ALCAM activated leukocyte cell adhesion molecule
AREG amphiregulin
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CD24 CD24 molecule
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
CLDN3 claudin 3
CLDN8 claudin 8
CREB1 cAMP responsive element binding protein 1
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EGR3 early growth response 3
ELF5 E74-like factor 5 (ets domain transcription factor)
EPCAM epithelial cell adhesion molecule
EREG epiregulin
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FOSL1 FOS-like antigen 1
GCH1 GTP cyclohydrolase 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
HBEGF heparin-binding EGF-like growth factor
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
IER3 immediate early response 3
IL1R2 interleukin 1 receptor, type II
KRT15 keratin 15, type I
KRT8 keratin 8, type II
LAMB3 laminin, beta 3
LEF1 lymphoid enhancer-binding factor 1
LTF lactotransferrin
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MYC v-myc avian myelocytomatosis viral oncogene homolog
NT5E 5'-nucleotidase, ecto (CD73)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PTGER4 prostaglandin E receptor 4 (subtype EP4)
RTN1 reticulon 1
S100A12 S100 calcium binding protein A12
SDC1 syndecan 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SPRY2 sprouty homolog 2 (Drosophila)
STEAP1 six transmembrane epithelial antigen of the prostate 1
STX1A syntaxin 1A (brain)