BRD-K05104363_PD-184352_MDAMB231_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

32 genes differentially expressed following the BRD-K05104363_PD-184352_MDAMB231_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
CP ceruloplasmin (ferroxidase)
DEPTOR DEP domain containing MTOR-interacting protein
FAM117A family with sequence similarity 117, member A
FHL1 four and a half LIM domains 1
FZD5 frizzled class receptor 5
IL1R1 interleukin 1 receptor, type I
LOX lysyl oxidase
MBNL2 muscleblind-like splicing regulator 2
MFAP5 microfibrillar associated protein 5
MN1 meningioma (disrupted in balanced translocation) 1
MT1M metallothionein 1M
MYL9 myosin, light chain 9, regulatory
OSR2 odd-skipped related transciption factor 2
PEX11A peroxisomal biogenesis factor 11 alpha
PIR pirin (iron-binding nuclear protein)
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC39A14 solute carrier family 39 (zinc transporter), member 14
SULF1 sulfatase 1
TAGLN transgelin
THBS2 thrombospondin 2
TMEM47 transmembrane protein 47
TPM2 tropomyosin 2 (beta)

decreased expression

Symbol Name
ETV1 ets variant 1
MMP1 matrix metallopeptidase 1
MMP9 matrix metallopeptidase 9
POLB polymerase (DNA directed), beta
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RRM2 ribonucleotide reductase M2
TM4SF1 transmembrane 4 L six family member 1
TMEM158 transmembrane protein 158 (gene/pseudogene)
UBE2S ubiquitin-conjugating enzyme E2S