BRD-K05104363_PD-184352_MCF7_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

99 genes differentially expressed following the BRD-K05104363_PD-184352_MCF7_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ANPEP alanyl (membrane) aminopeptidase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CD52 CD52 molecule
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHN1 chimerin 1
CLEC2B C-type lectin domain family 2, member B
COL8A2 collagen, type VIII, alpha 2
CSTA cystatin A (stefin A)
CSTF2T cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
CYTL1 cytokine-like 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHRS2 dehydrogenase/reductase (SDR family) member 2
DPYSL3 dihydropyrimidinase-like 3
EGR2 early growth response 2
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FAM129A family with sequence similarity 129, member A
FSCN1 fascin actin-bundling protein 1
GLUL glutamate-ammonia ligase
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HOPX HOP homeobox
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MSMB microseminoprotein, beta-
NRBF2 nuclear receptor binding factor 2
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIP prolactin-induced protein
PLAU plasminogen activator, urokinase
PNKP polynucleotide kinase 3'-phosphatase
PROM1 prominin 1
RGS1 regulator of G-protein signaling 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SEPW1 selenoprotein W, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A6 solute carrier family 16, member 6
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TDO2 tryptophan 2,3-dioxygenase
TMC5 transmembrane channel-like 5
TMSB15A thymosin beta 15a
TPSAB1 tryptase alpha/beta 1
TPSB2 tryptase beta 2 (gene/pseudogene)
TSPAN8 tetraspanin 8

decreased expression

Symbol Name
ADM adrenomedullin
ADRB2 adrenoceptor beta 2, surface
AK4 adenylate kinase 4
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1
CA12 carbonic anhydrase XII
CX3CL1 chemokine (C-X3-C motif) ligand 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DUSP4 dual specificity phosphatase 4
EGR1 early growth response 1
ENO1 enolase 1, (alpha)
ENO2 enolase 2 (gamma, neuronal)
F12 coagulation factor XII (Hageman factor)
FAS Fas cell surface death receptor
FGF13 fibroblast growth factor 13
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GSTZ1 glutathione S-transferase zeta 1
HLA-B major histocompatibility complex, class I, B
HOXC6 homeobox C6
IFI44L interferon-induced protein 44-like
IGFBP5 insulin-like growth factor binding protein 5
ISG15 ISG15 ubiquitin-like modifier
ISG20 interferon stimulated exonuclease gene 20kDa
ITM2C integral membrane protein 2C
KLF4 Kruppel-like factor 4 (gut)
MPPED2 metallophosphoesterase domain containing 2
MT1E metallothionein 1E
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1X metallothionein 1X
MYLK myosin light chain kinase
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
OPHN1 oligophrenin 1
PEG10 paternally expressed 10
PGAM1 phosphoglycerate mutase 1 (brain)
PPAP2A phosphatidic acid phosphatase type 2A
PTX3 pentraxin 3, long
RHOB ras homolog family member B
RND3 Rho family GTPase 3
RPL37A ribosomal protein L37a
SCD5 stearoyl-CoA desaturase 5
SCN3A sodium channel, voltage gated, type III alpha subunit
SFRP1 secreted frizzled-related protein 1
SOD2 superoxide dismutase 2, mitochondrial
SPP1 secreted phosphoprotein 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLR4 toll-like receptor 4
UFM1 ubiquitin-fold modifier 1
VEGFA vascular endothelial growth factor A