BRD-K05104363_PD-184352_MCF10A_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

85 genes differentially expressed following the BRD-K05104363_PD-184352_MCF10A_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
CXCL5 chemokine (C-X-C motif) ligand 5
FGFR3 fibroblast growth factor receptor 3
H2BFS H2B histone family, member S (pseudogene)
HDAC6 histone deacetylase 6
HIST1H2BK histone cluster 1, H2bk
HOPX HOP homeobox
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HSPB8 heat shock 22kDa protein 8
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
KDM3A lysine (K)-specific demethylase 3A
LONP2 lon peptidase 2, peroxisomal
LTBP1 latent transforming growth factor beta binding protein 1
MMP12 matrix metallopeptidase 12
NOTCH3 notch 3
NPR3 natriuretic peptide receptor 3
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated)
RDX radixin
REEP1 receptor accessory protein 1
RGS1 regulator of G-protein signaling 1
RGS2 regulator of G-protein signaling 2
S100A7 S100 calcium binding protein A7
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SPP1 secreted phosphoprotein 1
TCF4 transcription factor 4
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM45A transmembrane protein 45A
TSC22D3 TSC22 domain family, member 3

decreased expression

Symbol Name
ANPEP alanyl (membrane) aminopeptidase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEMIP cell migration inducing protein, hyaluronan binding
CLDN4 claudin 4
COLEC12 collectin sub-family member 12
CSNK1E casein kinase 1, epsilon
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
EGR2 early growth response 2
EGR3 early growth response 3
EMP1 epithelial membrane protein 1
ETV1 ets variant 1
F3 coagulation factor III (thromboplastin, tissue factor)
FOSL1 FOS-like antigen 1
G0S2 G0/G1 switch 2
GDF15 growth differentiation factor 15
HBEGF heparin-binding EGF-like growth factor
HES1 hes family bHLH transcription factor 1
HMGA2 high mobility group AT-hook 2
HNMT histamine N-methyltransferase
IER2 immediate early response 2
IER3 immediate early response 3
JCHAIN joining chain of multimeric IgA and IgM
LGALS3 lectin, galactoside-binding, soluble, 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K3 mitogen-activated protein kinase kinase 3
MLPH melanophilin
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NT5E 5'-nucleotidase, ecto (CD73)
PDGFA platelet-derived growth factor alpha polypeptide
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAC8 placenta-specific 8
PLAT plasminogen activator, tissue
RNASE4 ribonuclease, RNase A family, 4
SATB1 SATB homeobox 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SOX9 SRY (sex determining region Y)-box 9
SPRY2 sprouty homolog 2 (Drosophila)
STEAP1 six transmembrane epithelial antigen of the prostate 1
STK39 serine threonine kinase 39
STX1A syntaxin 1A (brain)
TF transferrin
ZFP36L1 ZFP36 ring finger protein-like 1