BRD-K05104363_PD-184352_MCF10A_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

163 genes differentially expressed following the BRD-K05104363_PD-184352_MCF10A_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ABLIM1 actin binding LIM protein 1
ACTG2 actin, gamma 2, smooth muscle, enteric
AHNAK AHNAK nucleoprotein
AHNAK2 AHNAK nucleoprotein 2
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ASPN asporin
ASS1 argininosuccinate synthase 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BCL6 B-cell CLL/lymphoma 6
BID BH3 interacting domain death agonist
BLVRB biliverdin reductase B
BST2 bone marrow stromal cell antigen 2
C1S complement component 1, s subcomponent
C3 complement component 3
CAPN1 calpain 1, (mu/I) large subunit
CCL5 chemokine (C-C motif) ligand 5
CD14 CD14 molecule
CD24 CD24 molecule
CD8A CD8a molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CFB complement factor B
CLIC3 chloride intracellular channel 3
CNN1 calponin 1, basic, smooth muscle
COL1A1 collagen, type I, alpha 1
COL1A2 collagen, type I, alpha 2
CXCL5 chemokine (C-X-C motif) ligand 5
DCN decorin
DEPTOR DEP domain containing MTOR-interacting protein
E2F2 E2F transcription factor 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EFNA1 ephrin-A1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ESR1 estrogen receptor 1
FBLN1 fibulin 1
FILIP1L filamin A interacting protein 1-like
FOXN3 forkhead box N3
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GLUL glutamate-ammonia ligase
GM2A GM2 ganglioside activator
GOLGA8A golgin A8 family, member A
GPNMB glycoprotein (transmembrane) nmb
GUSBP3 glucuronidase, beta pseudogene 3
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HIST1H2AC histone cluster 1, H2ac
HIST1H2BK histone cluster 1, H2bk
HOXC6 homeobox C6
HSPB8 heat shock 22kDa protein 8
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IL1RN interleukin 1 receptor antagonist
ISG15 ISG15 ubiquitin-like modifier
JUP junction plakoglobin
KRT13 keratin 13, type I
KRT15 keratin 15, type I
KRT17 keratin 17, type I
KRT4 keratin 4, type II
KRT8 keratin 8, type II
LITAF lipopolysaccharide-induced TNF factor
LY75 lymphocyte antigen 75
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MEIS1 Meis homeobox 1
METTL7A methyltransferase like 7A
MFAP5 microfibrillar associated protein 5
MUC1 mucin 1, cell surface associated
MXRA5 matrix-remodelling associated 5
MYH11 myosin, heavy chain 11, smooth muscle
MYL9 myosin, light chain 9, regulatory
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUPR1 nuclear protein, transcriptional regulator, 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
ORAI3 ORAI calcium release-activated calcium modulator 3
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PI3 peptidase inhibitor 3, skin-derived
PLN phospholamban
PPL periplakin
PSAP prosaposin
PSENEN presenilin enhancer gamma secretase subunit
RAB25 RAB25, member RAS oncogene family
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RGS1 regulator of G-protein signaling 1
RSRP1 arginine/serine-rich protein 1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SPAG4 sperm associated antigen 4
SPINT1 serine peptidase inhibitor, Kunitz type 1
SULF1 sulfatase 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SULT1A2 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2
SYBU syntabulin (syntaxin-interacting)
SYNE2 spectrin repeat containing, nuclear envelope 2
TAGLN transgelin
TCEAL4 transcription elongation factor A (SII)-like 4
TMEM47 transmembrane protein 47
TNNC1 troponin C type 1 (slow)
TPM1 tropomyosin 1 (alpha)
TPM2 tropomyosin 2 (beta)
TRD T cell receptor delta locus
TRIM16 tripartite motif containing 16
TRIM22 tripartite motif containing 22
TRIM29 tripartite motif containing 29
TSC22D3 TSC22 domain family, member 3
TUSC3 tumor suppressor candidate 3
TXNIP thioredoxin interacting protein
UPK1B uroplakin 1B
VCAN versican
VGLL1 vestigial-like family member 1
WFDC2 WAP four-disulfide core domain 2

decreased expression

Symbol Name
AREG amphiregulin
ASPH aspartate beta-hydroxylase
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BMP2 bone morphogenetic protein 2
CDC25A cell division cycle 25A
CSNK1E casein kinase 1, epsilon
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EGR2 early growth response 2
EGR3 early growth response 3
EIF5 eukaryotic translation initiation factor 5
EREG epiregulin
ETV1 ets variant 1
FLRT3 fibronectin leucine rich transmembrane protein 3
FOSL1 FOS-like antigen 1
FST follistatin
GEM GTP binding protein overexpressed in skeletal muscle
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
H1F0 H1 histone family, member 0
HAS2 hyaluronan synthase 2
HBEGF heparin-binding EGF-like growth factor
HHEX hematopoietically expressed homeobox
HIST1H4C histone cluster 1, H4c
HMGA2 high mobility group AT-hook 2
IER3 immediate early response 3
IGHM immunoglobulin heavy constant mu
IL13RA2 interleukin 13 receptor, alpha 2
MCM5 minichromosome maintenance complex component 5
MGLL monoglyceride lipase
NOP56 NOP56 ribonucleoprotein
NPY neuropeptide Y
NT5E 5'-nucleotidase, ecto (CD73)
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAT plasminogen activator, tissue
PRSS3 protease, serine, 3
PTHLH parathyroid hormone-like hormone
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SOX9 SRY (sex determining region Y)-box 9
SPRY2 sprouty homolog 2 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SYNJ2 synaptojanin 2
TEX30 testis expressed 30
TMEM158 transmembrane protein 158 (gene/pseudogene)
UPP1 uridine phosphorylase 1
ZFP36L1 ZFP36 ring finger protein-like 1