BRD-K05104363_HY-50295_NPC_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-K05104363_HY-50295_NPC_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ATF3 activating transcription factor 3
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
BASP1 brain abundant, membrane attached signal protein 1
C8ORF4 chromosome 8 open reading frame 4
CD24 CD24 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CNN3 calponin 3, acidic
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRYAB crystallin, alpha B
CSRP1 cysteine and glycine-rich protein 1
CTBP1 C-terminal binding protein 1
CTSG cathepsin G
CXCL14 chemokine (C-X-C motif) ligand 14
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FBN2 fibrillin 2
FHL1 four and a half LIM domains 1
GLIPR1 GLI pathogenesis-related 1
HSPB8 heat shock 22kDa protein 8
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
LAPTM4B lysosomal protein transmembrane 4 beta
LTF lactotransferrin
MAP1B microtubule-associated protein 1B
MYL9 myosin, light chain 9, regulatory
NAMPT nicotinamide phosphoribosyltransferase
NEFL neurofilament, light polypeptide
PCCB propionyl CoA carboxylase, beta polypeptide
PCGF2 polycomb group ring finger 2
PDGFD platelet derived growth factor D
RHOB ras homolog family member B
S100A2 S100 calcium binding protein A2
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SRGN serglycin
STMN2 stathmin 2
TAGLN transgelin
TNC tenascin C
TPM1 tropomyosin 1 (alpha)
TSPAN7 tetraspanin 7
TUBB6 tubulin, beta 6 class V
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VAT1 vesicle amine transport 1
ZIC1 Zic family member 1

decreased expression

Symbol Name
AMIGO2 adhesion molecule with Ig-like domain 2
ANO1 anoctamin 1, calcium activated chloride channel
ARHGAP26 Rho GTPase activating protein 26
CCND2 cyclin D2
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ETV1 ets variant 1
HLA-DMA major histocompatibility complex, class II, DM alpha
IGFBP3 insulin-like growth factor binding protein 3
IL1RN interleukin 1 receptor antagonist
ITGB5 integrin, beta 5
LDHB lactate dehydrogenase B
MMP12 matrix metallopeptidase 12
MUC5B mucin 5B, oligomeric mucus/gel-forming
MYB v-myb avian myeloblastosis viral oncogene homolog
NBPF10 neuroblastoma breakpoint family, member 10
NT5E 5'-nucleotidase, ecto (CD73)
PEG3 paternally expressed 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFRP1 secreted frizzled-related protein 1
SPRY2 sprouty homolog 2 (Drosophila)
TES testin LIM domain protein
TESC tescalcin
TIMP3 TIMP metallopeptidase inhibitor 3
TRIB2 tribbles pseudokinase 2