BRD-K04853698_LDN-193189_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

88 genes differentially expressed following the BRD-K04853698_LDN-193189_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADCY9 adenylate cyclase 9
AQP1 aquaporin 1 (Colton blood group)
AQP3 aquaporin 3 (Gill blood group)
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
C1ORF115 chromosome 1 open reading frame 115
C4BPA complement component 4 binding protein, alpha
C8ORF4 chromosome 8 open reading frame 4
CA12 carbonic anhydrase XII
CADM1 cell adhesion molecule 1
CALR calreticulin
CD40 CD40 molecule, TNF receptor superfamily member 5
CD99 CD99 molecule
CNOT4 CCR4-NOT transcription complex, subunit 4
COLEC12 collectin sub-family member 12
CRABP1 cellular retinoic acid binding protein 1
CXCR4 chemokine (C-X-C motif) receptor 4
ENO2 enolase 2 (gamma, neuronal)
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
EVL Enah/Vasp-like
FADS1 fatty acid desaturase 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HMGN3 high mobility group nucleosomal binding domain 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL17RB interleukin 17 receptor B
IRX5 iroquois homeobox 5
KRT6A keratin 6A, type II
LAMP3 lysosomal-associated membrane protein 3
MAOA monoamine oxidase A
MKNK1 MAP kinase interacting serine/threonine kinase 1
PLAT plasminogen activator, tissue
POU2AF1 POU class 2 associating factor 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SDC3 syndecan 3
SELENBP1 selenium binding protein 1
SEPP1 selenoprotein P, plasma, 1
SFRP1 secreted frizzled-related protein 1
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SFTPC surfactant protein C
SFTPD surfactant protein D
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SPON1 spondin 1, extracellular matrix protein
SPON2 spondin 2, extracellular matrix protein
SPTSSA serine palmitoyltransferase, small subunit A
SSFA2 sperm specific antigen 2
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TFF3 trefoil factor 3 (intestinal)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBI transforming growth factor, beta-induced, 68kDa
TMEM45A transmembrane protein 45A
TNC tenascin C
TSPAN4 tetraspanin 4
TSPAN7 tetraspanin 7
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ACD adrenocortical dysplasia homolog (mouse)
ACTA2 actin, alpha 2, smooth muscle, aorta
AKAP12 A kinase (PRKA) anchor protein 12
CD24 CD24 molecule
COMP cartilage oligomeric matrix protein
CRISP3 cysteine-rich secretory protein 3
CTSG cathepsin G
DHRS2 dehydrogenase/reductase (SDR family) member 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa
KIAA1033 KIAA1033
LCN2 lipocalin 2
MARCKSL1 MARCKS-like 1
MMP7 matrix metallopeptidase 7
MYLK myosin light chain kinase
NEFH neurofilament, heavy polypeptide
NR2F6 nuclear receptor subfamily 2, group F, member 6
OPN3 opsin 3
PAN2 PAN2 poly(A) specific ribonuclease subunit
PEG3 paternally expressed 3
PSCA prostate stem cell antigen
S100P S100 calcium binding protein P
SATB1 SATB homeobox 1
SNAP25 synaptosomal-associated protein, 25kDa
SPARCL1 SPARC-like 1 (hevin)
SYNGR3 synaptogyrin 3
TJP2 tight junction protein 2
ZFPM2 zinc finger protein, FOG family member 2