BRD-K04853698_LDN-193189_HEPG2_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

82 genes differentially expressed following the BRD-K04853698_LDN-193189_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD2 abhydrolase domain containing 2
ACBD3 acyl-CoA binding domain containing 3
AMIGO2 adhesion molecule with Ig-like domain 2
APP amyloid beta (A4) precursor protein
CAST calpastatin
CD36 CD36 molecule (thrombospondin receptor)
CD9 CD9 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
COL11A1 collagen, type XI, alpha 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CTGF connective tissue growth factor
CX3CL1 chemokine (C-X3-C motif) ligand 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DUSP6 dual specificity phosphatase 6
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FAM198B family with sequence similarity 198, member B
G0S2 G0/G1 switch 2
ICAM1 intercellular adhesion molecule 1
IGFBP4 insulin-like growth factor binding protein 4
JMJD6 jumonji domain containing 6
KDM5D lysine (K)-specific demethylase 5D
KRT18 keratin 18, type I
LEF1 lymphoid enhancer-binding factor 1
LXN latexin
MARCKS myristoylated alanine-rich protein kinase C substrate
MARCKSL1 MARCKS-like 1
MLPH melanophilin
MUC5B mucin 5B, oligomeric mucus/gel-forming
PDGFC platelet derived growth factor C
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PLAT plasminogen activator, tissue
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNASET2 ribonuclease T2
SOX4 SRY (sex determining region Y)-box 4
TACSTD2 tumor-associated calcium signal transducer 2
TM4SF1 transmembrane 4 L six family member 1
TMPRSS2 transmembrane protease, serine 2
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TNS3 tensin 3
TRIB2 tribbles pseudokinase 2
VWF von Willebrand factor
WT1 Wilms tumor 1

decreased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
ASPA aspartoacylase
BEX1 brain expressed, X-linked 1
BLNK B-cell linker
CCND2 cyclin D2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CES1 carboxylesterase 1
CLIC4 chloride intracellular channel 4
COBL cordon-bleu WH2 repeat protein
CXCL9 chemokine (C-X-C motif) ligand 9
DAPK1 death-associated protein kinase 1
DIO1 deiodinase, iodothyronine, type I
DMD dystrophin
EML1 echinoderm microtubule associated protein like 1
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GLDC glycine dehydrogenase (decarboxylating)
GLUL glutamate-ammonia ligase
GRWD1 glutamate-rich WD repeat containing 1
GSTA1 glutathione S-transferase alpha 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ITM2A integral membrane protein 2A
KIAA0922 KIAA0922
MCM3 minichromosome maintenance complex component 3
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
RAB31 RAB31, member RAS oncogene family
REEP1 receptor accessory protein 1
RNF128 ring finger protein 128, E3 ubiquitin protein ligase
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SPINK1 serine peptidase inhibitor, Kazal type 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
VAV3 vav 3 guanine nucleotide exchange factor
XIST X inactive specific transcript (non-protein coding)