BRD-K04853698_LDN-193189_HA1E_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

92 genes differentially expressed following the BRD-K04853698_LDN-193189_HA1E_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ANXA3 annexin A3
ARHGAP29 Rho GTPase activating protein 29
ASS1 argininosuccinate synthase 1
CCL2 chemokine (C-C motif) ligand 2
CD47 CD47 molecule
CHI3L2 chitinase 3-like 2
CLDN7 claudin 7
CLU clusterin
COBL cordon-bleu WH2 repeat protein
CST3 cystatin C
CXCL8 chemokine (C-X-C motif) ligand 8
ELF1 E74-like factor 1 (ets domain transcription factor)
ERAP2 endoplasmic reticulum aminopeptidase 2
FAM129A family with sequence similarity 129, member A
FKBP5 FK506 binding protein 5
GBP1 guanylate binding protein 1, interferon-inducible
GSTZ1 glutathione S-transferase zeta 1
HSPH1 heat shock 105kDa/110kDa protein 1
ICAM1 intercellular adhesion molecule 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KRT19 keratin 19, type I
KRT5 keratin 5, type II
KRT7 keratin 7, type II
L1CAM L1 cell adhesion molecule
LAMB3 laminin, beta 3
LMO3 LIM domain only 3 (rhombotin-like 2)
MAOB monoamine oxidase B
MAX MYC associated factor X
MTUS1 microtubule associated tumor suppressor 1
OLFM4 olfactomedin 4
PCP4 Purkinje cell protein 4
PDLIM4 PDZ and LIM domain 4
PLA2G16 phospholipase A2, group XVI
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PTX3 pentraxin 3, long
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
S100A2 S100 calcium binding protein A2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SFN stratifin
SLPI secretory leukocyte peptidase inhibitor
SOX9 SRY (sex determining region Y)-box 9
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SYNE2 spectrin repeat containing, nuclear envelope 2
TACSTD2 tumor-associated calcium signal transducer 2
TM4SF1 transmembrane 4 L six family member 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
WFDC2 WAP four-disulfide core domain 2
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ACP5 acid phosphatase 5, tartrate resistant
ACSM3 acyl-CoA synthetase medium-chain family member 3
ADGRG1 adhesion G protein-coupled receptor G1
CA2 carbonic anhydrase II
CXCL14 chemokine (C-X-C motif) ligand 14
CYTIP cytohesin 1 interacting protein
DAPK1 death-associated protein kinase 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EPHA3 EPH receptor A3
GDF15 growth differentiation factor 15
GPM6B glycoprotein M6B
HBEGF heparin-binding EGF-like growth factor
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMG20B high mobility group 20B
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGF1R insulin-like growth factor 1 receptor
IGFBP3 insulin-like growth factor binding protein 3
IGKV4-1 immunoglobulin kappa variable 4-1
IVNS1ABP influenza virus NS1A binding protein
LRRC17 leucine rich repeat containing 17
LXN latexin
MAP7 microtubule-associated protein 7
MFAP3L microfibrillar-associated protein 3-like
MFSD12 major facilitator superfamily domain containing 12
NEB nebulin
NPTX2 neuronal pentraxin II
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NRIP1 nuclear receptor interacting protein 1
RDX radixin
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SULF1 sulfatase 1
THBS1 thrombospondin 1
TSPAN13 tetraspanin 13
VCAN versican
VEGFA vascular endothelial growth factor A