BRD-K04853698_LDN-193189_BT20_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K04853698_LDN-193189_BT20_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AKR1C1 aldo-keto reductase family 1, member C1
BAG3 BCL2-associated athanogene 3
BHMT2 betaine--homocysteine S-methyltransferase 2
C1ORF115 chromosome 1 open reading frame 115
CBR3 carbonyl reductase 3
CELF2 CUGBP, Elav-like family member 2
CEP76 centrosomal protein 76kDa
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1
CLDN10 claudin 10
CPE carboxypeptidase E
CREG1 cellular repressor of E1A-stimulated genes 1
CST1 cystatin SN
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
ECD ecdysoneless homolog (Drosophila)
EML3 echinoderm microtubule associated protein like 3
EPM2AIP1 EPM2A (laforin) interacting protein 1
FUCA1 fucosidase, alpha-L- 1, tissue
GCLM glutamate-cysteine ligase, modifier subunit
GDF15 growth differentiation factor 15
GLUL glutamate-ammonia ligase
HIST1H1C histone cluster 1, H1c
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
JMJD6 jumonji domain containing 6
MKNK1 MAP kinase interacting serine/threonine kinase 1
PIR pirin (iron-binding nuclear protein)
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PMP22 peripheral myelin protein 22
PRUNE2 prune homolog 2 (Drosophila)
RNMT RNA (guanine-7-) methyltransferase
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SHROOM2 shroom family member 2
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SQSTM1 sequestosome 1
SRGN serglycin
SYT1 synaptotagmin I
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
WT1 Wilms tumor 1

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALOX5 arachidonate 5-lipoxygenase
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
ANXA3 annexin A3
ASPN asporin
ATF5 activating transcription factor 5
ATM ATM serine/threonine kinase
CD24 CD24 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CKAP4 cytoskeleton-associated protein 4
CLIC3 chloride intracellular channel 3
COL5A1 collagen, type V, alpha 1
CPM carboxypeptidase M
CXCL14 chemokine (C-X-C motif) ligand 14
DKK3 dickkopf WNT signaling pathway inhibitor 3
ECM1 extracellular matrix protein 1
EGFR epidermal growth factor receptor
FABP4 fatty acid binding protein 4, adipocyte
FBN2 fibrillin 2
FZD6 frizzled class receptor 6
G0S2 G0/G1 switch 2
GNAS GNAS complex locus
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER3 immediate early response 3
IFI6 interferon, alpha-inducible protein 6
ITGA6 integrin, alpha 6
JUNB jun B proto-oncogene
KRT17 keratin 17, type I
LOX lysyl oxidase
LUM lumican
LYPLA1 lysophospholipase I
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MARCKS myristoylated alanine-rich protein kinase C substrate
MMP11 matrix metallopeptidase 11
MRPS16 mitochondrial ribosomal protein S16
NPIPB3 nuclear pore complex interacting protein family, member B3
NRIP1 nuclear receptor interacting protein 1
NT5E 5'-nucleotidase, ecto (CD73)
PDGFC platelet derived growth factor C
PLBD1 phospholipase B domain containing 1
PLSCR3 phospholipid scramblase 3
PRDX2 peroxiredoxin 2
PRMT1 protein arginine methyltransferase 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
TACSTD2 tumor-associated calcium signal transducer 2
TAGLN transgelin
TFPI2 tissue factor pathway inhibitor 2
THBS1 thrombospondin 1
TIMP3 TIMP metallopeptidase inhibitor 3
TPM1 tropomyosin 1 (alpha)
TUBB2A tubulin, beta 2A class IIa
TUBB6 tubulin, beta 6 class V
TUSC3 tumor suppressor candidate 3
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
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