BRD-K04833372_GSK-1904529A_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

97 genes differentially expressed following the BRD-K04833372_GSK-1904529A_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
ACKR3 atypical chemokine receptor 3
AKR1C3 aldo-keto reductase family 1, member C3
ATP9A ATPase, class II, type 9A
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CBR3 carbonyl reductase 3
CCNG2 cyclin G2
CD99 CD99 molecule
CHST1 carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
CTSF cathepsin F
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM63A family with sequence similarity 63, member A
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXO4 forkhead box O4
FXYD3 FXYD domain containing ion transport regulator 3
GSTM3 glutathione S-transferase mu 3 (brain)
HBP1 HMG-box transcription factor 1
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HIST1H2BG histone cluster 1, H2bg
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IFITM1 interferon induced transmembrane protein 1
JUND jun D proto-oncogene
KIZ kizuna centrosomal protein
LAMP2 lysosomal-associated membrane protein 2
LAMP5 lysosomal-associated membrane protein family, member 5
MAN1A1 mannosidase, alpha, class 1A, member 1
MARCKSL1 MARCKS-like 1
METTL7A methyltransferase like 7A
MMP7 matrix metallopeptidase 7
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1M metallothionein 1M
MT1X metallothionein 1X
MX2 MX dynamin-like GTPase 2
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PNRC1 proline-rich nuclear receptor coactivator 1
QPCT glutaminyl-peptide cyclotransferase
QPRT quinolinate phosphoribosyltransferase
RAB40B RAB40B, member RAS oncogene family
RALGDS ral guanine nucleotide dissociation stimulator
RFX5 regulatory factor X, 5 (influences HLA class II expression)
SAT1 spermidine/spermine N1-acetyltransferase 1
SEPP1 selenoprotein P, plasma, 1
SKAP2 src kinase associated phosphoprotein 2
SSFA2 sperm specific antigen 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFBR3 transforming growth factor, beta receptor III
TGIF1 TGFB-induced factor homeobox 1
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TXNIP thioredoxin interacting protein
VCAM1 vascular cell adhesion molecule 1

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AK1 adenylate kinase 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
CCNE2 cyclin E2
CD52 CD52 molecule
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDC6 cell division cycle 6
CSTA cystatin A (stefin A)
EREG epiregulin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FCN1 ficolin (collagen/fibrinogen domain containing) 1
G0S2 G0/G1 switch 2
GLIPR1 GLI pathogenesis-related 1
HTRA1 HtrA serine peptidase 1
KRT14 keratin 14, type I
LTF lactotransferrin
MCM10 minichromosome maintenance complex component 10
MET MET proto-oncogene, receptor tyrosine kinase
MXRA7 matrix-remodelling associated 7
NEB nebulin
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PCDH9 protocadherin 9
PCOLCE2 procollagen C-endopeptidase enhancer 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PITX1 paired-like homeodomain 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
S100A2 S100 calcium binding protein A2
SDC2 syndecan 2
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLPI secretory leukocyte peptidase inhibitor
TREM1 triggering receptor expressed on myeloid cells 1
TUBB6 tubulin, beta 6 class V