BRD-K04833372_GSK-1904529A_MCF7_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

55 genes differentially expressed following the BRD-K04833372_GSK-1904529A_MCF7_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AKR1C3 aldo-keto reductase family 1, member C3
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
BCAT1 branched chain amino-acid transaminase 1, cytosolic
C10ORF10 chromosome 10 open reading frame 10
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD163 CD163 molecule
CD44 CD44 molecule (Indian blood group)
CFI complement factor I
CHN1 chimerin 1
CP ceruloplasmin (ferroxidase)
EFNA1 ephrin-A1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPS8 epidermal growth factor receptor pathway substrate 8
GAS6 growth arrest-specific 6
GLUL glutamate-ammonia ligase
GPNMB glycoprotein (transmembrane) nmb
GRB7 growth factor receptor-bound protein 7
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGL immunoglobulin lambda locus
IL1R1 interleukin 1 receptor, type I
KLHL24 kelch-like family member 24
KYNU kynureninase
MAN1A1 mannosidase, alpha, class 1A, member 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PDGFD platelet derived growth factor D
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SEPP1 selenoprotein P, plasma, 1
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TRIM2 tripartite motif containing 2
TSPAN7 tetraspanin 7
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
ANXA5 annexin A5
CDC25A cell division cycle 25A
CKAP4 cytoskeleton-associated protein 4
COTL1 coactosin-like F-actin binding protein 1
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
HSPB8 heat shock 22kDa protein 8
KDM5D lysine (K)-specific demethylase 5D
LAGE3 L antigen family, member 3
LTF lactotransferrin
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
S100P S100 calcium binding protein P
SORD sorbitol dehydrogenase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TSPAN8 tetraspanin 8