BRD-K04833372_GSK-1904529A_HME1_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

68 genes differentially expressed following the BRD-K04833372_GSK-1904529A_HME1_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
CA12 carbonic anhydrase XII
CD48 CD48 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CLU clusterin
CRYAB crystallin, alpha B
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
DHRS2 dehydrogenase/reductase (SDR family) member 2
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
F13A1 coagulation factor XIII, A1 polypeptide
FMO2 flavin containing monooxygenase 2 (non-functional)
GPX3 glutathione peroxidase 3
GSTM3 glutathione S-transferase mu 3 (brain)
HS2ST1 heparan sulfate 2-O-sulfotransferase 1
KRT23 keratin 23, type I
KRT7 keratin 7, type II
LBP lipopolysaccharide binding protein
MAN1A1 mannosidase, alpha, class 1A, member 1
MGP matrix Gla protein
NOS3 nitric oxide synthase 3 (endothelial cell)
OPN3 opsin 3
OXTR oxytocin receptor
PDE1A phosphodiesterase 1A, calmodulin-dependent
PEG3 paternally expressed 3
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PLAGL1 pleiomorphic adenoma gene-like 1
PTN pleiotrophin
RAP1GAP RAP1 GTPase activating protein
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RGCC regulator of cell cycle
SELL selectin L
SKAP2 src kinase associated phosphoprotein 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SYNGR3 synaptogyrin 3
TFF3 trefoil factor 3 (intestinal)
TIMP3 TIMP metallopeptidase inhibitor 3
TSC22D3 TSC22 domain family, member 3
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
AXL AXL receptor tyrosine kinase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD24 CD24 molecule
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
CHGB chromogranin B
COL4A6 collagen, type IV, alpha 6
CTBP2 C-terminal binding protein 2
CXCL13 chemokine (C-X-C motif) ligand 13
DPYSL3 dihydropyrimidinase-like 3
ESR1 estrogen receptor 1
FBXO21 F-box protein 21
GLIPR1 GLI pathogenesis-related 1
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLM1 golgi membrane protein 1
GSPT2 G1 to S phase transition 2
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KCTD12 potassium channel tetramerization domain containing 12
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NXN nucleoredoxin
SDC4 syndecan 4
SLC25A46 solute carrier family 25, member 46
TGFBI transforming growth factor, beta-induced, 68kDa
ZDHHC6 zinc finger, DHHC-type containing 6