BRD-K04695623_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K04695623_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
AGR2 anterior gradient 2
ARMCX3 armadillo repeat containing, X-linked 3
CDK2AP2 cyclin-dependent kinase 2 associated protein 2
CLIC4 chloride intracellular channel 4
DDIT4 DNA-damage-inducible transcript 4
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
FADS1 fatty acid desaturase 1
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GLRX glutaredoxin (thioltransferase)
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA13 heat shock protein 70kDa family, member 13
IGFBP5 insulin-like growth factor binding protein 5
INSIG1 insulin induced gene 1
LTBP1 latent transforming growth factor beta binding protein 1
NUCB2 nucleobindin 2
S100P S100 calcium binding protein P
SDF2L1 stromal cell-derived factor 2-like 1
SEC24D SEC24 family member D
SERP1 stress-associated endoplasmic reticulum protein 1
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC35B1 solute carrier family 35, member B1
SLC38A2 solute carrier family 38, member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SSR1 signal sequence receptor, alpha
TNC tenascin C
TXNIP thioredoxin interacting protein
ZBTB18 zinc finger and BTB domain containing 18

decreased expression

Symbol Name
BMP2 bone morphogenetic protein 2
C1QA complement component 1, q subcomponent, A chain
CLEC2B C-type lectin domain family 2, member B
CPE carboxypeptidase E
CYR61 cysteine-rich, angiogenic inducer, 61
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FHL1 four and a half LIM domains 1
IGFBP7 insulin-like growth factor binding protein 7
MTERF3 mitochondrial transcription termination factor 3
PAWR PRKC, apoptosis, WT1, regulator
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PTHLH parathyroid hormone-like hormone
RPIA ribose 5-phosphate isomerase A
SNX7 sorting nexin 7
TLE4 transducin-like enhancer of split 4
TLK2 tousled-like kinase 2