BRD-K04695623_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K04695623_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADIRF adipogenesis regulatory factor
ARMCX1 armadillo repeat containing, X-linked 1
ASNS asparagine synthetase (glutamine-hydrolyzing)
BEX4 brain expressed, X-linked 4
CA2 carbonic anhydrase II
CAPG capping protein (actin filament), gelsolin-like
CD200 CD200 molecule
CEMIP cell migration inducing protein, hyaluronan binding
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
FKBP11 FK506 binding protein 11, 19 kDa
GDF15 growth differentiation factor 15
GLRX glutaredoxin (thioltransferase)
GSTA1 glutathione S-transferase alpha 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
HMOX1 heme oxygenase 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HYOU1 hypoxia up-regulated 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV3-20 immunoglobulin kappa variable 3-20
IGKV4-1 immunoglobulin kappa variable 4-1
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
MAGEA3 melanoma antigen family A3
MAP7 microtubule-associated protein 7
MEST mesoderm specific transcript
MSLN mesothelin
MSMB microseminoprotein, beta-
NEFH neurofilament, heavy polypeptide
PDE4B phosphodiesterase 4B, cAMP-specific
PPIB peptidylprolyl isomerase B (cyclophilin B)
PRUNE2 prune homolog 2 (Drosophila)
PXDN peroxidasin
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100P S100 calcium binding protein P
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SDF2L1 stromal cell-derived factor 2-like 1
TMSB15A thymosin beta 15a
TPD52L1 tumor protein D52-like 1
TRIB3 tribbles pseudokinase 3
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
BCL2A1 BCL2-related protein A1
BST2 bone marrow stromal cell antigen 2
CADM1 cell adhesion molecule 1
CCND1 cyclin D1
DCBLD2 discoidin, CUB and LCCL domain containing 2
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
IFI44 interferon-induced protein 44
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IL1R1 interleukin 1 receptor, type I
KDM3A lysine (K)-specific demethylase 3A
KLF10 Kruppel-like factor 10
MSH6 mutS homolog 6
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
TLR4 toll-like receptor 4
TPX2 TPX2, microtubule-associated