BRD-K04548931_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K04548931_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA1 annexin A1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD36 CD36 molecule (thrombospondin receptor)
CETN2 centrin, EF-hand protein, 2
EMP1 epithelial membrane protein 1
HIST1H1C histone cluster 1, H1c
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
MDFIC MyoD family inhibitor domain containing
PON2 paraoxonase 2
RBKS ribokinase
RPS4Y1 ribosomal protein S4, Y-linked 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14
TMEM45A transmembrane protein 45A
VAMP3 vesicle-associated membrane protein 3

decreased expression

Symbol Name
CDCA4 cell division cycle associated 4
DLC1 DLC1 Rho GTPase activating protein
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FASTKD5 FAST kinase domains 5
GABPB1 GA binding protein transcription factor, beta subunit 1
HES1 hes family bHLH transcription factor 1
IER3 immediate early response 3
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOP56 NOP56 ribonucleoprotein
NXT1 nuclear transport factor 2-like export factor 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
POLR1D polymerase (RNA) I polypeptide D, 16kDa
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
TBX2 T-box 2
TGFBR3 transforming growth factor, beta receptor III
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1