BRD-K04534322_-666_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

44 genes differentially expressed following the BRD-K04534322_-666_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AREG amphiregulin
ASS1 argininosuccinate synthase 1
CCL20 chemokine (C-C motif) ligand 20
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DDIT4 DNA-damage-inducible transcript 4
FAM129A family with sequence similarity 129, member A
FBN2 fibrillin 2
FST follistatin
FTH1 ferritin, heavy polypeptide 1
H1F0 H1 histone family, member 0
HMOX1 heme oxygenase 1
IL1B interleukin 1, beta
KRT19 keratin 19, type I
MFAP5 microfibrillar associated protein 5
NDRG1 N-myc downstream regulated 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
S100P S100 calcium binding protein P
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SQSTM1 sequestosome 1
TPBG trophoblast glycoprotein
TST thiosulfate sulfurtransferase (rhodanese)
VEGFA vascular endothelial growth factor A

decreased expression

Symbol Name
CCNA2 cyclin A2
CD320 CD320 molecule
CENPA centromere protein A
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
EIF5A eukaryotic translation initiation factor 5A
FABP5 fatty acid binding protein 5 (psoriasis-associated)
HOXA10 homeobox A10
HOXC6 homeobox C6
KIF14 kinesin family member 14
KIF20A kinesin family member 20A
PBK PDZ binding kinase
PLK1 polo-like kinase 1
PWP1 PWP1 homolog (S. cerevisiae)
RPS11 ribosomal protein S11
SFPQ splicing factor proline/glutamine-rich
SNX10 sorting nexin 10
TOP2A topoisomerase (DNA) II alpha 170kDa
TUBB4B tubulin, beta 4B class IVb