BRD-K04534322_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

31 genes differentially expressed following the BRD-K04534322_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA1 annexin A1
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATF3 activating transcription factor 3
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
COMP cartilage oligomeric matrix protein
DDIT4 DNA-damage-inducible transcript 4
FTH1 ferritin, heavy polypeptide 1
HIST1H2AC histone cluster 1, H2ac
INSIG1 insulin induced gene 1
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5
MFAP5 microfibrillar associated protein 5
MYC v-myc avian myelocytomatosis viral oncogene homolog
NFIL3 nuclear factor, interleukin 3 regulated
NID2 nidogen 2 (osteonidogen)
NPTX2 neuronal pentraxin II
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SOD2 superoxide dismutase 2, mitochondrial
SSBP2 single-stranded DNA binding protein 2
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
BAG3 BCL2-associated athanogene 3
CA2 carbonic anhydrase II
CDC42 cell division cycle 42
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
NFIB nuclear factor I/B
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
TACSTD2 tumor-associated calcium signal transducer 2
TBX2 T-box 2
ZDHHC6 zinc finger, DHHC-type containing 6