BRD-K03857568_1-Methyl-3-nitro-4-p-tolylsulfanyl-1H-quinolin-2-one BRD-K03857568_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

43 genes differentially expressed following the BRD-K03857568_1-Methyl-3-nitro-4-p-tolylsulfanyl-1H-quinolin-2-one BRD-K03857568_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
CA2 carbonic anhydrase II
CASP7 caspase 7, apoptosis-related cysteine peptidase
CD14 CD14 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLCA4 chloride channel accessory 4
CRYAB crystallin, alpha B
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
GCLM glutamate-cysteine ligase, modifier subunit
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA2 heat shock 70kDa protein 2
HSPA4L heat shock 70kDa protein 4-like
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPB1 heat shock 27kDa protein 1
HSPB8 heat shock 22kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IL1R2 interleukin 1 receptor, type II
KLF4 Kruppel-like factor 4 (gut)
MIR22HG MIR22 host gene
NOTCH1 notch 1
PLK2 polo-like kinase 2
PPP1R15A protein phosphatase 1, regulatory subunit 15A
S100P S100 calcium binding protein P
SNAI2 snail family zinc finger 2
TCP1 t-complex 1
THBD thrombomodulin
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
ZFAND5 zinc finger, AN1-type domain 5

decreased expression

Symbol Name
ALCAM activated leukocyte cell adhesion molecule
CD200 CD200 molecule
DFNA5 deafness, autosomal dominant 5
PCP4 Purkinje cell protein 4
RTN1 reticulon 1