BRD-K03857568_1-Methyl-3-nitro-4-p-tolylsulfanyl-1H-quinolin-2-one BRD-K03857568_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

48 genes differentially expressed following the BRD-K03857568_1-Methyl-3-nitro-4-p-tolylsulfanyl-1H-quinolin-2-one BRD-K03857568_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AEBP1 AE binding protein 1
DCN decorin
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FOS FBJ murine osteosarcoma viral oncogene homolog
GMPR guanosine monophosphate reductase
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
JMJD6 jumonji domain containing 6
LMO2 LIM domain only 2 (rhombotin-like 1)
MXI1 MAX interactor 1, dimerization protein
NQO1 NAD(P)H dehydrogenase, quinone 1
PDLIM5 PDZ and LIM domain 5
PLIN2 perilipin 2
QPRT quinolinate phosphoribosyltransferase
RHOB ras homolog family member B
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SMAD3 SMAD family member 3
SRGN serglycin
TIPARP TCDD-inducible poly(ADP-ribose) polymerase
TSPYL5 TSPY-like 5
TXNRD1 thioredoxin reductase 1

decreased expression

Symbol Name
CCND2 cyclin D2
DKK1 dickkopf WNT signaling pathway inhibitor 1
ENC1 ectodermal-neural cortex 1 (with BTB domain)
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
IGHM immunoglobulin heavy constant mu
KRT17 keratin 17, type I
KRT19 keratin 19, type I
KRT23 keratin 23, type I
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
LMO4 LIM domain only 4
MUC5B mucin 5B, oligomeric mucus/gel-forming
RAD23B RAD23 homolog B (S. cerevisiae)
RBP4 retinol binding protein 4, plasma
RGS2 regulator of G-protein signaling 2
S100A2 S100 calcium binding protein A2
SDC4 syndecan 4
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SOX9 SRY (sex determining region Y)-box 9
TRIM29 tripartite motif containing 29
XIST X inactive specific transcript (non-protein coding)