BRD-K03829970_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

131 genes differentially expressed following the BRD-K03829970_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ATF3 activating transcription factor 3
ATP11B ATPase, class VI, type 11B
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CFB complement factor B
CHN2 chimerin 2
CLIC5 chloride intracellular channel 5
COL11A1 collagen, type XI, alpha 1
COL1A2 collagen, type I, alpha 2
CXCR4 chemokine (C-X-C motif) receptor 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DPYSL3 dihydropyrimidinase-like 3
DUSP10 dual specificity phosphatase 10
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EPYC epiphycan
FABP7 fatty acid binding protein 7, brain
FHL1 four and a half LIM domains 1
GADD45B growth arrest and DNA-damage-inducible, beta
GJA1 gap junction protein, alpha 1, 43kDa
GPM6A glycoprotein M6A
GRB10 growth factor receptor-bound protein 10
GSTA1 glutathione S-transferase alpha 1
H2AFV H2A histone family, member V
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-F major histocompatibility complex, class I, F
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)
IFITM3 interferon induced transmembrane protein 3
KDM5D lysine (K)-specific demethylase 5D
LAMP3 lysosomal-associated membrane protein 3
LAPTM5 lysosomal protein transmembrane 5
LOX lysyl oxidase
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MLF1 myeloid leukemia factor 1
MSN moesin
NR4A2 nuclear receptor subfamily 4, group A, member 2
NTS neurotensin
P3H2 prolyl 3-hydroxylase 2
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PDZK1IP1 PDZK1 interacting protein 1
PODXL podocalyxin-like
PXDN peroxidasin
RBM38 RNA binding motif protein 38
RGCC regulator of cell cycle
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RUNX3 runt-related transcription factor 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH3BGR SH3 domain binding glutamate-rich protein
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SPON1 spondin 1, extracellular matrix protein
SRGN serglycin
TGFBI transforming growth factor, beta-induced, 68kDa
THY1 Thy-1 cell surface antigen
TMEM158 transmembrane protein 158 (gene/pseudogene)
TMEM45A transmembrane protein 45A
TMEM47 transmembrane protein 47
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
USP9Y ubiquitin specific peptidase 9, Y-linked
VIM vimentin

decreased expression

Symbol Name
AGR2 anterior gradient 2
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARID1A AT rich interactive domain 1A (SWI-like)
BAMBI BMP and activin membrane-bound inhibitor
CANT1 calcium activated nucleotidase 1
CCNF cyclin F
CDCA4 cell division cycle associated 4
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
COL14A1 collagen, type XIV, alpha 1
DLC1 DLC1 Rho GTPase activating protein
EIF5 eukaryotic translation initiation factor 5
ESR1 estrogen receptor 1
EXOSC4 exosome component 4
FHL2 four and a half LIM domains 2
GABPB1 GA binding protein transcription factor, beta subunit 1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATA3 GATA binding protein 3
GNL3 guanine nucleotide binding protein-like 3 (nucleolar)
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HOXA5 homeobox A5
HSPA6 heat shock 70kDa protein 6 (HSP70B')
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRT7 keratin 7, type II
KYNU kynureninase
MAT2A methionine adenosyltransferase II, alpha
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH11 myosin, heavy chain 11, smooth muscle
NACA nascent polypeptide-associated complex alpha subunit
NCK1 NCK adaptor protein 1
NFIB nuclear factor I/B
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOP56 NOP56 ribonucleoprotein
NOTCH2NL notch 2 N-terminal like
NRIP1 nuclear receptor interacting protein 1
PARP2 poly (ADP-ribose) polymerase 2
PAXBP1 PAX3 and PAX7 binding protein 1
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLK1 polo-like kinase 1
PLK2 polo-like kinase 2
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
POLR1D polymerase (RNA) I polypeptide D, 16kDa
PON3 paraoxonase 3
RPL10 ribosomal protein L10
RPL17 ribosomal protein L17
SAMD4A sterile alpha motif domain containing 4A
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SMC1A structural maintenance of chromosomes 1A
SOX4 SRY (sex determining region Y)-box 4
SPDEF SAM pointed domain containing ETS transcription factor
STX1A syntaxin 1A (brain)
SYBU syntabulin (syntaxin-interacting)
TCERG1 transcription elongation regulator 1
TFPI2 tissue factor pathway inhibitor 2
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSKU tsukushi, small leucine rich proteoglycan
UBE2C ubiquitin-conjugating enzyme E2C
XBP1 X-box binding protein 1
ZNF451 zinc finger protein 451