BRD-K03736784_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

78 genes differentially expressed following the BRD-K03736784_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ATF4 activating transcription factor 4
CCR1 chemokine (C-C motif) receptor 1
CD163 CD163 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CTH cystathionine gamma-lyase
DDIT4 DNA-damage-inducible transcript 4
DEFB1 defensin, beta 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FABP7 fatty acid binding protein 7, brain
FOSL1 FOS-like antigen 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GPM6A glycoprotein M6A
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA12A heat shock 70kDa protein 12A
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFRD1 interferon-related developmental regulator 1
JMJD6 jumonji domain containing 6
KCTD5 potassium channel tetramerization domain containing 5
KLF4 Kruppel-like factor 4 (gut)
LEFTY1 left-right determination factor 1
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NDUFA4 NDUFA4, mitochondrial complex associated
NPTX2 neuronal pentraxin II
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PSAT1 phosphoserine aminotransferase 1
RPL38 ribosomal protein L38
RPS11 ribosomal protein S11
SATB2 SATB homeobox 2
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SORBS1 sorbin and SH3 domain containing 1
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TGFBI transforming growth factor, beta-induced, 68kDa
TSC22D3 TSC22 domain family, member 3
TXN thioredoxin

decreased expression

Symbol Name
AGTR1 angiotensin II receptor, type 1
BAMBI BMP and activin membrane-bound inhibitor
CA12 carbonic anhydrase XII
CDC20 cell division cycle 20
CHMP6 charged multivesicular body protein 6
ESR1 estrogen receptor 1
FBN2 fibrillin 2
FZD6 frizzled class receptor 6
GATA3 GATA binding protein 3
GBP1 guanylate binding protein 1, interferon-inducible
GRK5 G protein-coupled receptor kinase 5
HES1 hes family bHLH transcription factor 1
HOXC6 homeobox C6
HSPG2 heparan sulfate proteoglycan 2
IGF1R insulin-like growth factor 1 receptor
KRT15 keratin 15, type I
KRT7 keratin 7, type II
KRT81 keratin 81, type II
LRRC17 leucine rich repeat containing 17
MGP matrix Gla protein
MMP9 matrix metallopeptidase 9
MREG melanoregulin
MSL1 male-specific lethal 1 homolog (Drosophila)
NFIB nuclear factor I/B
NOV nephroblastoma overexpressed
NRIP1 nuclear receptor interacting protein 1
REG3A regenerating islet-derived 3 alpha
SMAD3 SMAD family member 3
SOX4 SRY (sex determining region Y)-box 4
SPDEF SAM pointed domain containing ETS transcription factor
SVIL supervillin
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFF1 trefoil factor 1