BRD-K03449891_foretinib_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

39 genes differentially expressed following the BRD-K03449891_foretinib_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
AGR2 anterior gradient 2
CD44 CD44 molecule (Indian blood group)
CD9 CD9 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
DDIT4 DNA-damage-inducible transcript 4
EFR3A EFR3 homolog A (S. cerevisiae)
FXYD2 FXYD domain containing ion transport regulator 2
GPNMB glycoprotein (transmembrane) nmb
HES1 hes family bHLH transcription factor 1
HIST1H2AC histone cluster 1, H2ac
HMG20B high mobility group 20B
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
MX2 MX dynamin-like GTPase 2
NDRG1 N-myc downstream regulated 1
NEFL neurofilament, light polypeptide
OLFM4 olfactomedin 4
PRAME preferentially expressed antigen in melanoma
PRUNE2 prune homolog 2 (Drosophila)
RHOQ ras homolog family member Q
S100A14 S100 calcium binding protein A14
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SLC22A18 solute carrier family 22, member 18
TBX3 T-box 3
TFF3 trefoil factor 3 (intestinal)

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADRB2 adrenoceptor beta 2, surface
CA2 carbonic anhydrase II
CCNE2 cyclin E2
CD36 CD36 molecule (thrombospondin receptor)
ENO1 enolase 1, (alpha)
LOX lysyl oxidase
SLBP stem-loop binding protein
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
XK X-linked Kx blood group