BRD-K03406345_azacitidine_PC3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K03406345_azacitidine_PC3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADGRG6 adhesion G protein-coupled receptor G6
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APOD apolipoprotein D
ARPP19 cAMP-regulated phosphoprotein, 19kDa
BEX4 brain expressed, X-linked 4
BLNK B-cell linker
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD24 CD24 molecule
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CTGF connective tissue growth factor
CXCL10 chemokine (C-X-C motif) ligand 10
DLK1 delta-like 1 homolog (Drosophila)
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
FRZB frizzled-related protein
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GATA2 GATA binding protein 2
GRN granulin
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
KIAA0226L KIAA0226-like
KLF10 Kruppel-like factor 10
LGALS4 lectin, galactoside-binding, soluble, 4
LYN LYN proto-oncogene, Src family tyrosine kinase
MAMLD1 mastermind-like domain containing 1
MBD4 methyl-CpG binding domain protein 4
MET MET proto-oncogene, receptor tyrosine kinase
MXRA7 matrix-remodelling associated 7
PEG10 paternally expressed 10
PENK proenkephalin
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STAT1 signal transducer and activator of transcription 1, 91kDa
TGFBI transforming growth factor, beta-induced, 68kDa
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
USP1 ubiquitin specific peptidase 1
WEE1 WEE1 G2 checkpoint kinase

decreased expression

Symbol Name
ALDOA aldolase A, fructose-bisphosphate
AQP1 aquaporin 1 (Colton blood group)
COL6A3 collagen, type VI, alpha 3
COTL1 coactosin-like F-actin binding protein 1
CXCL14 chemokine (C-X-C motif) ligand 14
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MMP12 matrix metallopeptidase 12
NRP1 neuropilin 1
NTS neurotensin
PLAT plasminogen activator, tissue
POSTN periostin, osteoblast specific factor
PRDX2 peroxiredoxin 2
S100A2 S100 calcium binding protein A2
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SRGN serglycin
TNC tenascin C
TOX3 TOX high mobility group box family member 3
WNT5A wingless-type MMTV integration site family, member 5A