BRD-K03406345_azacitidine_MCF7_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

67 genes differentially expressed following the BRD-K03406345_azacitidine_MCF7_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
CALD1 caldesmon 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
EMX2 empty spiracles homeobox 2
FAM129A family with sequence similarity 129, member A
FGFR3 fibroblast growth factor receptor 3
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GDF15 growth differentiation factor 15
GJA1 gap junction protein, alpha 1, 43kDa
GLUL glutamate-ammonia ligase
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGFBP7 insulin-like growth factor binding protein 7
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM5D lysine (K)-specific demethylase 5D
LAMP5 lysosomal-associated membrane protein family, member 5
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
MAP1B microtubule-associated protein 1B
MYH11 myosin, heavy chain 11, smooth muscle
NAV3 neuron navigator 3
NUPR1 nuclear protein, transcriptional regulator, 1
PLA1A phospholipase A1 member A
PPAP2B phosphatidic acid phosphatase type 2B
RCAN2 regulator of calcineurin 2
RGS4 regulator of G-protein signaling 4
RPS4Y1 ribosomal protein S4, Y-linked 1
SCGB2A1 secretoglobin, family 2A, member 1
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SPRY4 sprouty homolog 4 (Drosophila)
SQSTM1 sequestosome 1
STAT1 signal transducer and activator of transcription 1, 91kDa
TAGLN transgelin
TCFL5 transcription factor-like 5 (basic helix-loop-helix)
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
VCAM1 vascular cell adhesion molecule 1
VIM vimentin
ZCCHC24 zinc finger, CCHC domain containing 24

decreased expression

Symbol Name
ANXA1 annexin A1
ANXA3 annexin A3
C20ORF24 chromosome 20 open reading frame 24
CAPNS1 calpain, small subunit 1
CAV2 caveolin 2
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDA cytidine deaminase
CREG1 cellular repressor of E1A-stimulated genes 1
DAPK1 death-associated protein kinase 1
HMG20B high mobility group 20B
LAMB3 laminin, beta 3
LPL lipoprotein lipase
MXRA5 matrix-remodelling associated 5
N4BP2L2 NEDD4 binding protein 2-like 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRIP1 nuclear receptor interacting protein 1
NRN1 neuritin 1
OPN3 opsin 3
PRKCB protein kinase C, beta
PXMP2 peroxisomal membrane protein 2, 22kDa
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TM4SF1 transmembrane 4 L six family member 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TSPAN13 tetraspanin 13
YBX3 Y box binding protein 3