BRD-K03063480_PF-477736_SKBR3_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

75 genes differentially expressed following the BRD-K03063480_PF-477736_SKBR3_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACTG2 actin, gamma 2, smooth muscle, enteric
APOD apolipoprotein D
ATF3 activating transcription factor 3
AURKA aurora kinase A
C6ORF62 chromosome 6 open reading frame 62
CCL20 chemokine (C-C motif) ligand 20
CD83 CD83 molecule
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CSNK1A1 casein kinase 1, alpha 1
CSTA cystatin A (stefin A)
EGFR epidermal growth factor receptor
GDF15 growth differentiation factor 15
GREB1 growth regulation by estrogen in breast cancer 1
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BD histone cluster 1, H2bd
HIST1H2BF histone cluster 1, H2bf
HIST1H2BK histone cluster 1, H2bk
HOPX HOP homeobox
ICAM1 intercellular adhesion molecule 1
IER5 immediate early response 5
IGFBP5 insulin-like growth factor binding protein 5
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL1R1 interleukin 1 receptor, type I
JUNB jun B proto-oncogene
KIF20A kinesin family member 20A
KRT23 keratin 23, type I
LCN2 lipocalin 2
MMP9 matrix metallopeptidase 9
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
OLFM1 olfactomedin 1
PCNA proliferating cell nuclear antigen
PEG3 paternally expressed 3
PHGDH phosphoglycerate dehydrogenase
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
RHOBTB3 Rho-related BTB domain containing 3
SCGB2A1 secretoglobin, family 2A, member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP1 secreted frizzled-related protein 1
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
STC2 stanniocalcin 2
TBC1D31 TBC1 domain family, member 31
TBX3 T-box 3
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa
TIMP1 TIMP metallopeptidase inhibitor 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRD T cell receptor delta locus
TSC22D1 TSC22 domain family, member 1
TUBB2A tubulin, beta 2A class IIa
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)

decreased expression

Symbol Name
ANOS1 anosmin 1
APP amyloid beta (A4) precursor protein
BMI1 BMI1 proto-oncogene, polycomb ring finger
COL11A1 collagen, type XI, alpha 1
CPB1 carboxypeptidase B1 (tissue)
CXCL14 chemokine (C-X-C motif) ligand 14
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
HEBP1 heme binding protein 1
LAPTM4B lysosomal protein transmembrane 4 beta
MAGEA3 melanoma antigen family A3
MBP myelin basic protein
MFAP2 microfibrillar-associated protein 2
NEBL nebulette
NREP neuronal regeneration related protein
PAX2 paired box 2
PBX1 pre-B-cell leukemia homeobox 1
PRKCA protein kinase C, alpha
RGS1 regulator of G-protein signaling 1
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
SPP1 secreted phosphoprotein 1
SSBP2 single-stranded DNA binding protein 2
TCF4 transcription factor 4
TOP2B topoisomerase (DNA) II beta 180kDa