BRD-K03063480_PF-477736_HCC515_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

140 genes differentially expressed following the BRD-K03063480_PF-477736_HCC515_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AARS alanyl-tRNA synthetase
ABHD4 abhydrolase domain containing 4
ALG13 ALG13, UDP-N-acetylglucosaminyltransferase subunit
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ASNS asparagine synthetase (glutamine-hydrolyzing)
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
ATF4 activating transcription factor 4
ATP11B ATPase, class VI, type 11B
C6ORF48 chromosome 6 open reading frame 48
CARS cysteinyl-tRNA synthetase
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DDIT3 DNA-damage-inducible transcript 3
EFS embryonal Fyn-associated substrate
EGR1 early growth response 1
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FRY furry homolog (Drosophila)
GADD45A growth arrest and DNA-damage-inducible, alpha
GOLGA8H golgin A8 family, member H
IER5 immediate early response 5
JUN jun proto-oncogene
LOC399491
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPC1 Niemann-Pick disease, type C1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PPFIBP2 PTPRF interacting protein, binding protein 2 (liprin beta 2)
PSAT1 phosphoserine aminotransferase 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SOX11 SRY (sex determining region Y)-box 11
SSR4 signal sequence receptor, delta
STK38L serine/threonine kinase 38 like
TCEA2 transcription elongation factor A (SII), 2
TESC tescalcin
TSC22D3 TSC22 domain family, member 3
TSPAN4 tetraspanin 4
TXNIP thioredoxin interacting protein
VNN1 vanin 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZFP36 ZFP36 ring finger protein

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
AKAP7 A kinase (PRKA) anchor protein 7
ANXA2 annexin A2
ANXA2P2 annexin A2 pseudogene 2
ARL4C ADP-ribosylation factor-like 4C
ATP1B3 ATPase, Na+/K+ transporting, beta 3 polypeptide
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
BICC1 BicC family RNA binding protein 1
CAPN2 calpain 2, (m/II) large subunit
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CCL2 chemokine (C-C motif) ligand 2
CCNA2 cyclin A2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CNN3 calponin 3, acidic
COL15A1 collagen, type XV, alpha 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
CP ceruloplasmin (ferroxidase)
CPOX coproporphyrinogen oxidase
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DLD dihydrolipoamide dehydrogenase
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DPYSL2 dihydropyrimidinase-like 2
EMP1 epithelial membrane protein 1
F11R F11 receptor
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSTL1 follistatin-like 1
FXYD3 FXYD domain containing ion transport regulator 3
GJA1 gap junction protein, alpha 1, 43kDa
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HP haptoglobin
HS3ST1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP3 insulin-like growth factor binding protein 3
IL7R interleukin 7 receptor
IQGAP1 IQ motif containing GTPase activating protein 1
KIAA0101 KIAA0101
KPNB1 karyopherin (importin) beta 1
KRT19 keratin 19, type I
LAMA4 laminin, alpha 4
LAMB1 laminin, beta 1
LEF1 lymphoid enhancer-binding factor 1
LMNB1 lamin B1
MELK maternal embryonic leucine zipper kinase
MSLN mesothelin
MTUS1 microtubule associated tumor suppressor 1
MUC16 mucin 16, cell surface associated
NRIP1 nuclear receptor interacting protein 1
PGAM1 phosphoglycerate mutase 1 (brain)
PI3 peptidase inhibitor 3, skin-derived
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PON2 paraoxonase 2
PPARG peroxisome proliferator-activated receptor gamma
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRSS23 protease, serine, 23
PSD3 pleckstrin and Sec7 domain containing 3
PSPH phosphoserine phosphatase
PTP4A2 protein tyrosine phosphatase type IVA, member 2
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RRM2 ribonucleotide reductase M2
S100A6 S100 calcium binding protein A6
S100A7 S100 calcium binding protein A7
SCGB2A1 secretoglobin, family 2A, member 1
SDC2 syndecan 2
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SPON1 spondin 1, extracellular matrix protein
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
TBC1D4 TBC1 domain family, member 4
TFF3 trefoil factor 3 (intestinal)
TFRC transferrin receptor
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TMEM97 transmembrane protein 97
TPI1 triosephosphate isomerase 1
TPR translocated promoter region, nuclear basket protein
TUBB tubulin, beta class I
TUBB6 tubulin, beta 6 class V
TYMS thymidylate synthetase
WSB2 WD repeat and SOCS box containing 2
ZFPM2 zinc finger protein, FOG family member 2
ZWINT ZW10 interacting kinetochore protein