BRD-K03015355_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

34 genes differentially expressed following the BRD-K03015355_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
ANGPTL2 angiopoietin-like 2
AREG amphiregulin
ARMCX1 armadillo repeat containing, X-linked 1
BTG2 BTG family, member 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CYTIP cytohesin 1 interacting protein
DUSP4 dual specificity phosphatase 4
FAM69A family with sequence similarity 69, member A
FTH1 ferritin, heavy polypeptide 1
GREM1 gremlin 1, DAN family BMP antagonist
NEB nebulin
PDE4B phosphodiesterase 4B, cAMP-specific
PPP1R3C protein phosphatase 1, regulatory subunit 3C
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
TBX3 T-box 3
XIST X inactive specific transcript (non-protein coding)

decreased expression

Symbol Name
AKAP12 A kinase (PRKA) anchor protein 12
CD59 CD59 molecule, complement regulatory protein
CLU clusterin
EIF5A eukaryotic translation initiation factor 5A
HMGA2 high mobility group AT-hook 2
KLF6 Kruppel-like factor 6
LAPTM4B lysosomal protein transmembrane 4 beta
MARCKS myristoylated alanine-rich protein kinase C substrate
PRSS23 protease, serine, 23
SRPX sushi-repeat containing protein, X-linked
SYBU syntabulin (syntaxin-interacting)
TGFBI transforming growth factor, beta-induced, 68kDa
TM4SF1 transmembrane 4 L six family member 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TPM1 tropomyosin 1 (alpha)