BRD-K02965346_SU-11274_HS578T_3_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

65 genes differentially expressed following the BRD-K02965346_SU-11274_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
CLU clusterin
CXCL5 chemokine (C-X-C motif) ligand 5
DAPK1 death-associated protein kinase 1
E2F2 E2F transcription factor 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGFR2 fibroblast growth factor receptor 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
HSPB8 heat shock 22kDa protein 8
KIAA1033 KIAA1033
LTF lactotransferrin
MMP7 matrix metallopeptidase 7
MTCL1 microtubule crosslinking factor 1
NNMT nicotinamide N-methyltransferase
NTS neurotensin
PDZK1 PDZ domain containing 1
PDZK1IP1 PDZK1 interacting protein 1
SCGB2A1 secretoglobin, family 2A, member 1
SST somatostatin
SYT1 synaptotagmin I
TM4SF4 transmembrane 4 L six family member 4
TYMP thymidine phosphorylase

decreased expression

Symbol Name
ADGRF5 adhesion G protein-coupled receptor F5
ALCAM activated leukocyte cell adhesion molecule
ARMCX1 armadillo repeat containing, X-linked 1
BEX4 brain expressed, X-linked 4
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCL20 chemokine (C-C motif) ligand 20
CCND2 cyclin D2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CTSH cathepsin H
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
EGFL6 EGF-like-domain, multiple 6
GATA3 GATA binding protein 3
GNAS GNAS complex locus
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HIST1H4H histone cluster 1, H4h
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
LAMB3 laminin, beta 3
LTBP2 latent transforming growth factor beta binding protein 2
LUM lumican
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MYO1D myosin ID
NRIP1 nuclear receptor interacting protein 1
PDZD2 PDZ domain containing 2
PEG10 paternally expressed 10
PEG3 paternally expressed 3
POU2AF1 POU class 2 associating factor 1
PRAME preferentially expressed antigen in melanoma
PRKCH protein kinase C, eta
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
SCG5 secretogranin V
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SFTPA2 surfactant protein A2
SOX11 SRY (sex determining region Y)-box 11
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM30B transmembrane protein 30B
TSPAN7 tetraspanin 7
ZBTB10 zinc finger and BTB domain containing 10