BRD-K02950022_BMS 299897_VCAP_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

30 genes differentially expressed following the BRD-K02950022_BMS 299897_VCAP_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANKRD10 ankyrin repeat domain 10
ANO1 anoctamin 1, calcium activated chloride channel
BASP1 brain abundant, membrane attached signal protein 1
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
FGFR2 fibroblast growth factor receptor 2
GOLGA8A golgin A8 family, member A
GOLGA8B golgin A8 family, member B
GOLM1 golgi membrane protein 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IRS2 insulin receptor substrate 2
LITAF lipopolysaccharide-induced TNF factor
MSLN mesothelin
RFX5 regulatory factor X, 5 (influences HLA class II expression)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNNT1 troponin T type 1 (skeletal, slow)
TRIM2 tripartite motif containing 2

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHNAK2 AHNAK nucleoprotein 2
CDV3 CDV3 homolog (mouse)
DAPK1 death-associated protein kinase 1
DHRS2 dehydrogenase/reductase (SDR family) member 2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FASTKD5 FAST kinase domains 5
FGFR3 fibroblast growth factor receptor 3
IGL immunoglobulin lambda locus
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
SIRT3 sirtuin 3
UPP1 uridine phosphorylase 1