BRD-K02680176_Clofilium tosylate_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

45 genes differentially expressed following the BRD-K02680176_Clofilium tosylate_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALB albumin
CXCL8 chemokine (C-X-C motif) ligand 8
DDIT4 DNA-damage-inducible transcript 4
FLNB filamin B, beta
HK2 hexokinase 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
ORM1 orosomucoid 1
RHOB ras homolog family member B
TESC tescalcin
TFF3 trefoil factor 3 (intestinal)
TM4SF4 transmembrane 4 L six family member 4

decreased expression

Symbol Name
ACTN1 actinin, alpha 1
ARMCX1 armadillo repeat containing, X-linked 1
ARPP19 cAMP-regulated phosphoprotein, 19kDa
CAV2 caveolin 2
CCNB2 cyclin B2
CD44 CD44 molecule (Indian blood group)
CSTA cystatin A (stefin A)
CYCS cytochrome c, somatic
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
EIF4A1 eukaryotic translation initiation factor 4A1
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
FHL1 four and a half LIM domains 1
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
GULP1 GULP, engulfment adaptor PTB domain containing 1
INSIG1 insulin induced gene 1
LXN latexin
MAN1A1 mannosidase, alpha, class 1A, member 1
MSMB microseminoprotein, beta-
MYBPC1 myosin binding protein C, slow type
NOV nephroblastoma overexpressed
OAT ornithine aminotransferase
ODC1 ornithine decarboxylase 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit
PRPF4 pre-mRNA processing factor 4
SGK1 serum/glucocorticoid regulated kinase 1
SLC25A32 solute carrier family 25 (mitochondrial folate carrier), member 32
THBS1 thrombospondin 1
TSPYL5 TSPY-like 5
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta