BRD-K02581333_Protein Tyrosine Phosphatase Inhibitor IV_VCAP_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

38 genes differentially expressed following the BRD-K02581333_Protein Tyrosine Phosphatase Inhibitor IV_VCAP_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
GLRX glutaredoxin (thioltransferase)
IGFBP5 insulin-like growth factor binding protein 5
LGALS1 lectin, galactoside-binding, soluble, 1
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PROM1 prominin 1
SFRP1 secreted frizzled-related protein 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SORBS2 sorbin and SH3 domain containing 2
TMEM110 transmembrane protein 110
TMEM158 transmembrane protein 158 (gene/pseudogene)

decreased expression

Symbol Name
CCND1 cyclin D1
CDKN2A cyclin-dependent kinase inhibitor 2A
CYTL1 cytokine-like 1
DEFB1 defensin, beta 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
KCTD12 potassium channel tetramerization domain containing 12
LAPTM4B lysosomal protein transmembrane 4 beta
LYPD1 LY6/PLAUR domain containing 1
MARCKS myristoylated alanine-rich protein kinase C substrate
MFSD10 major facilitator superfamily domain containing 10
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NUP62 nucleoporin 62kDa
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
RPL27A ribosomal protein L27a
RPL37A ribosomal protein L37a
RPS11 ribosomal protein S11
RPS21 ribosomal protein S21
SET SET nuclear proto-oncogene
SLC35F2 solute carrier family 35, member F2
SPINK1 serine peptidase inhibitor, Kazal type 1
STAB1 stabilin 1
TSPAN3 tetraspanin 3
WT1 Wilms tumor 1