BRD-K02581333_Protein Tyrosine Phosphatase Inhibitor IV_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

22 genes differentially expressed following the BRD-K02581333_Protein Tyrosine Phosphatase Inhibitor IV_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
CA12 carbonic anhydrase XII
CD40 CD40 molecule, TNF receptor superfamily member 5
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CPB1 carboxypeptidase B1 (tissue)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
HIST1H2AC histone cluster 1, H2ac
OPN3 opsin 3
PFKM phosphofructokinase, muscle
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SPRED2 sprouty-related, EVH1 domain containing 2
TSPYL5 TSPY-like 5

decreased expression

Symbol Name
ASS1 argininosuccinate synthase 1
CBR3 carbonyl reductase 3
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
MYH11 myosin, heavy chain 11, smooth muscle
OXTR oxytocin receptor
PIP prolactin-induced protein
PTN pleiotrophin
TUBB2A tubulin, beta 2A class IIa
TYRP1 tyrosinase-related protein 1