BRD-K02581333_Protein Tyrosine Phosphatase Inhibitor IV_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

24 genes differentially expressed following the BRD-K02581333_Protein Tyrosine Phosphatase Inhibitor IV_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARG2 arginase 2
CAST calpastatin
CCNA1 cyclin A1
OSBPL10 oxysterol binding protein-like 10
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
SHB Src homology 2 domain containing adaptor protein B
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SPON2 spondin 2, extracellular matrix protein
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
BHLHE40 basic helix-loop-helix family, member e40
CCND1 cyclin D1
DUSP4 dual specificity phosphatase 4
FAM46A family with sequence similarity 46, member A
LTBP3 latent transforming growth factor beta binding protein 3
NME4 NME/NM23 nucleoside diphosphate kinase 4
PEBP1 phosphatidylethanolamine binding protein 1
PFKL phosphofructokinase, liver
PIP prolactin-induced protein
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
TYRP1 tyrosinase-related protein 1
ZBTB20 zinc finger and BTB domain containing 20