BRD-K01877528_TL_HRAS26 BRD-K01877528_PC3_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K01877528_TL_HRAS26 BRD-K01877528_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AQP3 aquaporin 3 (Gill blood group)
ATF3 activating transcription factor 3
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COCH cochlin
CSRP1 cysteine and glycine-rich protein 1
CXCL2 chemokine (C-X-C motif) ligand 2
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DSP desmoplakin
DUSP4 dual specificity phosphatase 4
FBN2 fibrillin 2
H1F0 H1 histone family, member 0
HBEGF heparin-binding EGF-like growth factor
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
IER3 immediate early response 3
IGHD immunoglobulin heavy constant delta
IL32 interleukin 32
IL6 interleukin 6
JUNB jun B proto-oncogene
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
LMO4 LIM domain only 4
MKNK2 MAP kinase interacting serine/threonine kinase 2
MSX1 msh homeobox 1
OXSR1 oxidative stress responsive 1
PLAUR plasminogen activator, urokinase receptor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RGS2 regulator of G-protein signaling 2
RPS4Y1 ribosomal protein S4, Y-linked 1
S100P S100 calcium binding protein P
SIK1 salt-inducible kinase 1
SPARCL1 SPARC-like 1 (hevin)
SPRY2 sprouty homolog 2 (Drosophila)
SQSTM1 sequestosome 1
TKT transketolase
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNIP1 TNFAIP3 interacting protein 1

decreased expression

Symbol Name
CD200 CD200 molecule
DPP4 dipeptidyl-peptidase 4
DPYSL3 dihydropyrimidinase-like 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
LAMA4 laminin, alpha 4
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PLAC8 placenta-specific 8
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SOX11 SRY (sex determining region Y)-box 11