BRD-K01877528_TL_HRAS26 BRD-K01877528_HEPG2_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

57 genes differentially expressed following the BRD-K01877528_TL_HRAS26 BRD-K01877528_HEPG2_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
ALOX5 arachidonate 5-lipoxygenase
AQP1 aquaporin 1 (Colton blood group)
BLNK B-cell linker
C1QA complement component 1, q subcomponent, A chain
C1QB complement component 1, q subcomponent, B chain
CLDN3 claudin 3
COLEC12 collectin sub-family member 12
DDIT4 DNA-damage-inducible transcript 4
EGFR epidermal growth factor receptor
EPCAM epithelial cell adhesion molecule
F13A1 coagulation factor XIII, A1 polypeptide
FBN2 fibrillin 2
FCGBP Fc fragment of IgG binding protein
FTH1 ferritin, heavy polypeptide 1
GCLC glutamate-cysteine ligase, catalytic subunit
HMOX1 heme oxygenase 1
JUN jun proto-oncogene
KIAA0226L KIAA0226-like
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MUC16 mucin 16, cell surface associated
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PTN pleiotrophin
RGCC regulator of cell cycle
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNASE6 ribonuclease, RNase A family, k6
SFN stratifin
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SPARCL1 SPARC-like 1 (hevin)
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TPBG trophoblast glycoprotein
TWIST1 twist family bHLH transcription factor 1
TXNIP thioredoxin interacting protein

decreased expression

Symbol Name
CCNB2 cyclin B2
CTSC cathepsin C
CYR61 cysteine-rich, angiogenic inducer, 61
DHCR24 24-dehydrocholesterol reductase
DHRS2 dehydrogenase/reductase (SDR family) member 2
DPYSL2 dihydropyrimidinase-like 2
DUSP6 dual specificity phosphatase 6
FN1 fibronectin 1
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
IER3 immediate early response 3
LDLR low density lipoprotein receptor
MARCKS myristoylated alanine-rich protein kinase C substrate
MTUS1 microtubule associated tumor suppressor 1
NOP16 NOP16 nucleolar protein
NREP neuronal regeneration related protein
NRIP1 nuclear receptor interacting protein 1
NUP98 nucleoporin 98kDa
PDLIM2 PDZ and LIM domain 2 (mystique)
PMM2 phosphomannomutase 2
PNP purine nucleoside phosphorylase
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)