BRD-K01436366_XMD-1150_SKBR3_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

112 genes differentially expressed following the BRD-K01436366_XMD-1150_SKBR3_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALCAM activated leukocyte cell adhesion molecule
ALDOC aldolase C, fructose-bisphosphate
AREG amphiregulin
ARHGAP29 Rho GTPase activating protein 29
AUTS2 autism susceptibility candidate 2
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like
CD9 CD9 molecule
CERS6 ceramide synthase 6
CXORF57 chromosome X open reading frame 57
CYB5A cytochrome b5 type A (microsomal)
DFNA5 deafness, autosomal dominant 5
DHCR24 24-dehydrocholesterol reductase
DLK1 delta-like 1 homolog (Drosophila)
DMXL2 Dmx-like 2
DSE dermatan sulfate epimerase
EREG epiregulin
FGFR2 fibroblast growth factor receptor 2
FOLR1 folate receptor 1 (adult)
GATA2 GATA binding protein 2
GOLGA8B golgin A8 family, member B
GRB10 growth factor receptor-bound protein 10
GRN granulin
H2BFS H2B histone family, member S (pseudogene)
HIST1H2BK histone cluster 1, H2bk
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
ITGAV integrin, alpha V
JAG1 jagged 1
MAN1A1 mannosidase, alpha, class 1A, member 1
MXRA7 matrix-remodelling associated 7
MYO6 myosin VI
NAGK N-acetylglucosamine kinase
NKTR natural killer cell triggering receptor
NPIPB3 nuclear pore complex interacting protein family, member B3
NRGN neurogranin (protein kinase C substrate, RC3)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PYGL phosphorylase, glycogen, liver
SAT1 spermidine/spermine N1-acetyltransferase 1
SRSF6 serine/arginine-rich splicing factor 6
STAB1 stabilin 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TRA2A transformer 2 alpha homolog (Drosophila)
TSPAN13 tetraspanin 13

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ANXA1 annexin A1
ASPN asporin
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
CCL2 chemokine (C-C motif) ligand 2
CDH19 cadherin 19, type 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL15A1 collagen, type XV, alpha 1
COL3A1 collagen, type III, alpha 1
CRYAB crystallin, alpha B
CSRP2 cysteine and glycine-rich protein 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
CYBA cytochrome b-245, alpha polypeptide
E2F2 E2F transcription factor 2
EDNRB endothelin receptor type B
ENOPH1 enolase-phosphatase 1
EPB41L3 erythrocyte membrane protein band 4.1-like 3
FABP4 fatty acid binding protein 4, adipocyte
FAM129A family with sequence similarity 129, member A
FKBP11 FK506 binding protein 11, 19 kDa
FMOD fibromodulin
FXYD3 FXYD domain containing ion transport regulator 3
FZD7 frizzled class receptor 7
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GBP2 guanylate binding protein 2, interferon-inducible
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GPM6B glycoprotein M6B
GRIA2 glutamate receptor, ionotropic, AMPA 2
HK2 hexokinase 2
HOXA5 homeobox A5
HSPB8 heat shock 22kDa protein 8
ICAM3 intercellular adhesion molecule 3
IFRD2 interferon-related developmental regulator 2
IGF1 insulin-like growth factor 1 (somatomedin C)
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
KIAA0101 KIAA0101
LAMA4 laminin, alpha 4
LAMP5 lysosomal-associated membrane protein family, member 5
LTF lactotransferrin
MAL mal, T-cell differentiation protein
MGP matrix Gla protein
MUC5B mucin 5B, oligomeric mucus/gel-forming
NPR3 natriuretic peptide receptor 3
PLAC8 placenta-specific 8
POSTN periostin, osteoblast specific factor
PPAP2A phosphatidic acid phosphatase type 2A
PROM1 prominin 1
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PYCR1 pyrroline-5-carboxylate reductase 1
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RGS5 regulator of G-protein signaling 5
S100P S100 calcium binding protein P
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SORD sorbitol dehydrogenase
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TGFB3 transforming growth factor, beta 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRD T cell receptor delta locus
TRIB2 tribbles pseudokinase 2
TSPAN8 tetraspanin 8