BRD-K01436366_XMD-1150_MDAMB231_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K01436366_XMD-1150_MDAMB231_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
CA2 carbonic anhydrase II
CCL20 chemokine (C-C motif) ligand 20
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEMIP cell migration inducing protein, hyaluronan binding
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
EGR1 early growth response 1
FGFR4 fibroblast growth factor receptor 4
GSTT1 glutathione S-transferase theta 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL1R2 interleukin 1 receptor, type II
INSIG1 insulin induced gene 1
PLCB4 phospholipase C, beta 4
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTPRE protein tyrosine phosphatase, receptor type, E
RGS2 regulator of G-protein signaling 2
SDC2 syndecan 2
SGK1 serum/glucocorticoid regulated kinase 1
SLC38A1 solute carrier family 38, member 1
THAP11 THAP domain containing 11
TOB1 transducer of ERBB2, 1
ZNF331 zinc finger protein 331

decreased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ADRB2 adrenoceptor beta 2, surface
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BEX1 brain expressed, X-linked 1
BMP4 bone morphogenetic protein 4
CCND2 cyclin D2
CD24 CD24 molecule
COL4A2 collagen, type IV, alpha 2
DCN decorin
E2F2 E2F transcription factor 2
EGFR epidermal growth factor receptor
EPHA3 EPH receptor A3
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FRZB frizzled-related protein
GBP1 guanylate binding protein 1, interferon-inducible
GJA1 gap junction protein, alpha 1, 43kDa
GLI2 GLI family zinc finger 2
IFI16 interferon, gamma-inducible protein 16
IGF1 insulin-like growth factor 1 (somatomedin C)
KRT19 keratin 19, type I
KRT7 keratin 7, type II
LDHB lactate dehydrogenase B
LTF lactotransferrin
MUC1 mucin 1, cell surface associated
NAV3 neuron navigator 3
NRG1 neuregulin 1
PTCH1 patched 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTN pleiotrophin
RHOF ras homolog family member F (in filopodia)
ROR1 receptor tyrosine kinase-like orphan receptor 1
SCGB2A2 secretoglobin, family 2A, member 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SETBP1 SET binding protein 1
SFRP1 secreted frizzled-related protein 1
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
TACSTD2 tumor-associated calcium signal transducer 2
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
TRIP6 thyroid hormone receptor interactor 6
ZNF185 zinc finger protein 185 (LIM domain)