BRD-K01436366_XMD-1150_HS578T_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

56 genes differentially expressed following the BRD-K01436366_XMD-1150_HS578T_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
APOC1 apolipoprotein C-I
ASPN asporin
C6ORF48 chromosome 6 open reading frame 48
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CELF2 CUGBP, Elav-like family member 2
CLDN3 claudin 3
CLEC2B C-type lectin domain family 2, member B
COL11A1 collagen, type XI, alpha 1
CTSK cathepsin K
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DCN decorin
FCGBP Fc fragment of IgG binding protein
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
HIST1H1C histone cluster 1, H1c
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
PON3 paraoxonase 3
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
VNN1 vanin 1
ZFP36 ZFP36 ring finger protein
ZIC1 Zic family member 1

decreased expression

Symbol Name
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CD36 CD36 molecule (thrombospondin receptor)
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3
COL4A2 collagen, type IV, alpha 2
CPA3 carboxypeptidase A3 (mast cell)
CXCL8 chemokine (C-X-C motif) ligand 8
DACH1 dachshund family transcription factor 1
DHRS3 dehydrogenase/reductase (SDR family) member 3
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
GATA3 GATA binding protein 3
GDF15 growth differentiation factor 15
GRB7 growth factor receptor-bound protein 7
HOXA10 homeobox A10
HOXB2 homeobox B2
HOXB7 homeobox B7
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KEAP1 kelch-like ECH-associated protein 1
LAMA3 laminin, alpha 3
MME membrane metallo-endopeptidase
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PRPF4 pre-mRNA processing factor 4
RGCC regulator of cell cycle
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SORBS2 sorbin and SH3 domain containing 2
SPAG4 sperm associated antigen 4
SPINK1 serine peptidase inhibitor, Kazal type 1
TBL1X transducin (beta)-like 1X-linked
TNC tenascin C
VWF von Willebrand factor