BRD-K01436366_XMD-1150_HS578T_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

146 genes differentially expressed following the BRD-K01436366_XMD-1150_HS578T_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADRB2 adrenoceptor beta 2, surface
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ARG2 arginase 2
BLNK B-cell linker
BTG2 BTG family, member 2
C14ORF132 chromosome 14 open reading frame 132
C7 complement component 7
C9ORF16 chromosome 9 open reading frame 16
CCDC85B coiled-coil domain containing 85B
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
COL2A1 collagen, type II, alpha 1
CRP C-reactive protein, pentraxin-related
CXADR coxsackie virus and adenovirus receptor
DKK3 dickkopf WNT signaling pathway inhibitor 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EGR1 early growth response 1
FAM134B family with sequence similarity 134, member B
FBXO21 F-box protein 21
FHOD3 formin homology 2 domain containing 3
FLRT2 fibronectin leucine rich transmembrane protein 2
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GOLM1 golgi membrane protein 1
GPX2 glutathione peroxidase 2
GRB7 growth factor receptor-bound protein 7
HIST1H1C histone cluster 1, H1c
HIST1H2AC histone cluster 1, H2ac
HIST1H2BD histone cluster 1, H2bd
HMOX1 heme oxygenase 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI6 interferon, alpha-inducible protein 6
IL13RA2 interleukin 13 receptor, alpha 2
ISYNA1 inositol-3-phosphate synthase 1
ITGA6 integrin, alpha 6
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
LPAR6 lysophosphatidic acid receptor 6
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAN1C1 mannosidase, alpha, class 1C, member 1
MAOA monoamine oxidase A
MOXD1 monooxygenase, DBH-like 1
MYO6 myosin VI
NGRN neugrin, neurite outgrowth associated
NR2F2 nuclear receptor subfamily 2, group F, member 2
ORM1 orosomucoid 1
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PCDH9 protocadherin 9
PCOLCE2 procollagen C-endopeptidase enhancer 2
PLIN2 perilipin 2
PLS1 plastin 1
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PYCARD PYD and CARD domain containing
RAB4A RAB4A, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
SEPP1 selenoprotein P, plasma, 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SLIT2 slit homolog 2 (Drosophila)
SSFA2 sperm specific antigen 2
SST somatostatin
STAR steroidogenic acute regulatory protein
STXBP2 syntaxin binding protein 2
SYBU syntabulin (syntaxin-interacting)
UBXN4 UBX domain protein 4
VNN1 vanin 1
ZNF423 zinc finger protein 423

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTN1 actinin, alpha 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANPEP alanyl (membrane) aminopeptidase
ANXA1 annexin A1
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
BASP1 brain abundant, membrane attached signal protein 1
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
CALD1 caldesmon 1
CCL2 chemokine (C-C motif) ligand 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLU clusterin
CNN1 calponin 1, basic, smooth muscle
CST7 cystatin F (leukocystatin)
CXCL12 chemokine (C-X-C motif) ligand 12
DCK deoxycytidine kinase
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
EDN1 endothelin 1
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GBP1 guanylate binding protein 1, interferon-inducible
GLIPR1 GLI pathogenesis-related 1
IFITM1 interferon induced transmembrane protein 1
IFRD2 interferon-related developmental regulator 2
IGFBP3 insulin-like growth factor binding protein 3
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
INHBA inhibin, beta A
ITK IL2-inducible T-cell kinase
JADE2 jade family PHD finger 2
KLF6 Kruppel-like factor 6
KRT14 keratin 14, type I
KRT15 keratin 15, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6B keratin 6B, type II
KRT7 keratin 7, type II
KRT81 keratin 81, type II
MAP7 microtubule-associated protein 7
MCTP1 multiple C2 domains, transmembrane 1
MGAM maltase-glucoamylase
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MLPH melanophilin
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MYOF myoferlin
NNMT nicotinamide N-methyltransferase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
OXTR oxytocin receptor
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
RCAN1 regulator of calcineurin 1
RFC2 replication factor C (activator 1) 2, 40kDa
S100A11 S100 calcium binding protein A11
S100P S100 calcium binding protein P
SDC1 syndecan 1
SFN stratifin
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLPI secretory leukocyte peptidase inhibitor
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TACSTD2 tumor-associated calcium signal transducer 2
TARP TCR gamma alternate reading frame protein
TGM2 transglutaminase 2
TM4SF1 transmembrane 4 L six family member 1
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
TRIP6 thyroid hormone receptor interactor 6
UBE2C ubiquitin-conjugating enzyme E2C
WNT5A wingless-type MMTV integration site family, member 5A