BRD-K01436366_XMD-1150_HME1_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

100 genes differentially expressed following the BRD-K01436366_XMD-1150_HME1_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AK1 adenylate kinase 1
ATF5 activating transcription factor 5
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide
ATP6V0E2 ATPase, H+ transporting V0 subunit e2
BHLHE40 basic helix-loop-helix family, member e40
BTG2 BTG family, member 2
CD14 CD14 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP2 dual specificity phosphatase 2
EFNB2 ephrin-B2
EGR1 early growth response 1
EGR3 early growth response 3
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FUCA1 fucosidase, alpha-L- 1, tissue
GADD45B growth arrest and DNA-damage-inducible, beta
GEM GTP binding protein overexpressed in skeletal muscle
GPNMB glycoprotein (transmembrane) nmb
GSTT1 glutathione S-transferase theta 1
HIST2H2BE histone cluster 2, H2be
HSPA6 heat shock 70kDa protein 6 (HSP70B')
ICAM1 intercellular adhesion molecule 1
IER5 immediate early response 5
IFI27 interferon, alpha-inducible protein 27
IFI44L interferon-induced protein 44-like
IFI6 interferon, alpha-inducible protein 6
INSIG1 insulin induced gene 1
KIAA0226L KIAA0226-like
KLF10 Kruppel-like factor 10
LEF1 lymphoid enhancer-binding factor 1
LGMN legumain
LIF leukemia inhibitory factor
LPL lipoprotein lipase
MGP matrix Gla protein
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
SIK1 salt-inducible kinase 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SOBP sine oculis binding protein homolog (Drosophila)
SSBP2 single-stranded DNA binding protein 2
SSFA2 sperm specific antigen 2
TFRC transferrin receptor
TMEM2 transmembrane protein 2
TMEM259 transmembrane protein 259
TXNIP thioredoxin interacting protein
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANPEP alanyl (membrane) aminopeptidase
BEX1 brain expressed, X-linked 1
CA12 carbonic anhydrase XII
CBR3 carbonyl reductase 3
CCNE2 cyclin E2
CD40 CD40 molecule, TNF receptor superfamily member 5
CDH3 cadherin 3, type 1, P-cadherin (placental)
CRISP3 cysteine-rich secretory protein 3
CSTA cystatin A (stefin A)
DDX10 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
DKK1 dickkopf WNT signaling pathway inhibitor 1
DUSP3 dual specificity phosphatase 3
ELANE elastase, neutrophil expressed
EMX2 empty spiracles homeobox 2
FGF13 fibroblast growth factor 13
GABPB1 GA binding protein transcription factor, beta subunit 1
GTPBP8 GTP-binding protein 8 (putative)
ITM2C integral membrane protein 2C
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT13 keratin 13, type I
KRT5 keratin 5, type II
LXN latexin
MARCKS myristoylated alanine-rich protein kinase C substrate
MPO myeloperoxidase
NDN necdin, melanoma antigen (MAGE) family member
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
PLAC8 placenta-specific 8
PLEKHA5 pleckstrin homology domain containing, family A member 5
PPP1R16B protein phosphatase 1, regulatory subunit 16B
RDX radixin
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RNF144A ring finger protein 144A
S100A12 S100 calcium binding protein A12
S100P S100 calcium binding protein P
SMAD3 SMAD family member 3
SQRDL sulfide quinone reductase-like (yeast)
STC1 stanniocalcin 1
SYNGR1 synaptogyrin 1
TACSTD2 tumor-associated calcium signal transducer 2
TARP TCR gamma alternate reading frame protein
TEX10 testis expressed 10
TFF1 trefoil factor 1
TNS3 tensin 3
TSPYL5 TSPY-like 5
VANGL1 VANGL planar cell polarity protein 1
WBP5 WW domain binding protein 5
ZBTB20 zinc finger and BTB domain containing 20